ARUP's Laboratory Test Directory

0097222: Cortisol Urine Free by LC-MS/MS

Test Mnemonic: CORT UF
Methodology: Tandem Mass Spectrometry

Performed: Sun-Sat

Reported: 1-2 days

Specimen Required:  
Collect: 24-hour or random urine.  Refrigerate 24-hour sample during collection. 

Transport: 5 mL aliquot from a 24-hour collection at 2-8°C.  (Min: 1.5 mL)  Record total volume and collection time interval on transport tube and test request form.

Pediatric Collection/Transport: 1 mL aliquot from a 24-hour collection at 2-8°C. Record total volume and collection time interval on transport tube and test request form.

Unacceptable Conditions: Specimens with preservatives. Acidified specimens.

Stability: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 6 months

Reference Interval:
 
Test Name Female Male
Cortisol (µg/day) 3-8 years: Less than 18 µg/day
9-12 years: Less than 37 µg/day
13-17 years: Less than 56 µg/day
18 years and older: Less than 45 µg/day 		3-8 years: Less than 18 µg/day
9-12 years: Less than 37 µg/day
13-17 years: Less than 56 µg/day
18 years and older: Less than 60 µg/day
Cortisol (µg/g crt) Prepubertal: Less than 25 µg/g crt
18 years and older: Less than 45 µg/g crt
Pregnancy: Less than 59 µg/g crt 		Prepubertal: Less than 25 µg/g crt
18 years and older: Less than 32 µg/g crt
The urine cortisol-to-creatinine ratio will be reported when the urine collection is random, less than 20 hours, or the urine volume is less than 400 mL/24 hours.

Note:
Reference intervals based on literature from Taylor R.L. et al., Validation of a High-Throughput Liquid Chromatography-Tandem Mass Spectrometry Method for Urine Cortisol and Cortisone. Clinical Chemistry 2002; 48:1511-1519.

CPT Code(s):
82530

 

 

 
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