ARUP's Laboratory Test Directory

Lymphocyte Antigen Proliferation : 0096055
[ image for: Time Sensitive]
Time Sensitive
  


Mnemonic: LAPP

Methodology: Cell Culture
Performed: Tue-Fri
Reported: 9-10 days
Specimen Required: Patient Prep: Control specimen needs to be sent with patient specimen.

Collect: One 10 mL yellow (ACD Solution A) and one normal control in a 10 mL yellow (ACD Solution A) from a healthy unrelated individual.

Storage/Transport Temperature: 10 mL whole blood and 10 mL normal control in original collection tubes at 20-25°C. (Min: 7 mL whole blood and 7 mL normal control; Infant min: 3 mL whole blood and 7 mL normal control). LIVE LYMPHOCYTES REQUIRED. CRITICAL AMBIENT. Do not refrigerate or freeze.

Remarks: Patient and control samples must be collected within 48 hours of test performance.

Unacceptable Conditions: Refrigerated or frozen samples or samples in transport longer than 48 hours.

Stability (collection to initiation of testing): Ambient: 48 hours; Refrigerated: Unacceptable; Frozen: Unacceptable
Reference Interval:
By report
Interpretive Data: Candida and tetanus antigens are tested independently in lymphocyte culture. Lymphocyte proliferation in response to these antigens is determined by 3H-thymidine incorporation.

Results are reported as the counts per minute (CPM) antigen stimulated versus control cultures and a stimulation index (SI) which represents the ratio of mean CPM of the stimulated lymphocytes to the mean CPM of the unstimulated control.

Please refer to Statement B in the Compliance Statements section in the front of the Laboratory Test Directory.
Note: Interpretation comparing the patient results to the client normal control and the laboratory control will be provided by the medical director.
CPT Code(s): 86353 x2
Cross References: Antigen Proliferation, Lymphocytes
 
 

 

 

 
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