ARUP's Laboratory Test Directory

0096055: Lymphocyte Antigen Proliferation 

[ image for: Time Sensitive]
Time Sensitive
  

Test Mnemonic: LAPP
Methodology: Cell Culture

Performed: Tue-Fri

Reported: 9-10 days

Specimen Required:  
Collect: One 10 mL yellow (ACD Solution A) and one normal control in a 10 mL yellow (ACD Solution A) from a healthy unrelated individual.

Transport: 10 mL whole blood and 10 mL normal control in sterile containers at 20-25°C. LIVE LYMPHOCYTES REQUIRED. CRITICAL AMBIENT. Do not refrigerate or freeze.

Pediatric Collection/Transport: 3 mL whole blood (green, sodium heparin) and 3 mL whole blood (green, sodium heparin) normal control from a healthy unrelated individual in sterile containers at 20-25°C.  

Remarks: Patient and control samples must be collected within 48 hours of test performance.

Unacceptable Conditions: Refrigerated or frozen samples or samples in transport longer than 48 hours.

Stability: Ambient: 48 hours; Refrigerated: Unacceptable; Frozen: Unacceptable

Reference Interval:
By report

Interpretive Data:
Candida and tetanus antigens are tested independently in lymphocyte culture. Lymphocyte proliferation in response to these antigens is determined by 3H-thymidine incorporation.

Results are reported as the counts per minute (CPM) antigen stimulated versus control cultures and a stimulation index (SI) which represents the ratio of mean CPM of the stimulated lymphocytes to the mean CPM of the unstimulated control.

Please refer to Statement D in the Compliance Statements section in the front of the Laboratory Test Directory.



Note:
Interpretation comparing the patient results to the client normal control and the laboratory control will be provided by the medical director.

CPT Code(s):
86353 x2

 

 

 
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