ARUP's Laboratory Test Directory
| 0096055: Lymphocyte Antigen Proliferation |
![[ image for: Time Sensitive]](icon_1.jpg){kind=icon} | Time Sensitive |
| Test Mnemonic: LAPP | |
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Methodology: Cell Culture
Performed: Tue-Fri Reported: 9-10 days |
| Specimen Required: | |
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Collect: One 10 mL yellow (ACD Solution A) and one normal control in a 10 mL yellow (ACD Solution A) from a healthy unrelated individual.
Transport: 10 mL whole blood and 10 mL normal control in sterile containers at 20-25°C. LIVE LYMPHOCYTES REQUIRED. CRITICAL AMBIENT. Do not refrigerate or freeze. Pediatric Collection/Transport: 3 mL whole blood (green, sodium heparin) and 3 mL whole blood (green, sodium heparin) normal control from a healthy unrelated individual in sterile containers at 20-25°C. Remarks: Patient and control samples must be collected within 48 hours of test performance. Unacceptable Conditions: Refrigerated or frozen samples or samples in transport longer than 48 hours. Stability: Ambient: 48 hours; Refrigerated: Unacceptable; Frozen: Unacceptable |
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| Reference Interval: |
| By report |
| Interpretive Data: | |
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Candida and tetanus antigens are tested independently in lymphocyte culture. Lymphocyte proliferation in response to these antigens is determined by 3H-thymidine incorporation. Results are reported as the counts per minute (CPM) antigen stimulated versus control cultures and a stimulation index (SI) which represents the ratio of mean CPM of the stimulated lymphocytes to the mean CPM of the unstimulated control. Please refer to Statement D in the Compliance Statements section in the front of the Laboratory Test Directory. |
| Note: | |
| Interpretation comparing the patient results to the client normal control and the laboratory control will be provided by the medical director. |
| CPT Code(s): | |
| 86353 x2 |