ARUP's Laboratory Test Directory

B-Cell Immunodeficiency Profile : 0095940
[ image for: Time Sensitive]
Time Sensitive
  


Mnemonic: B-CELL

Methodology: Flow Cytometry
Performed: Sun-Sat
Reported: 1-3 days
Specimen Required: Collect: One 5 mL green (sodium or lithium heparin), lavender (EDTA), or pink (K2EDTA).

Storage/Transport Temperature: 5 mL whole blood at 20-25°C. (Min: 3 mL)

Remarks: CRITICAL AMBIENT. Specimens must be analyzed within 48 hours of collection.
New York State Clients:
EDTA specimens must be analyzed within 30 hours of collection. Heparin specimens must be analyzed within 48 hours of collection.


Unacceptable Conditions: Clotted, refrigerated, or frozen specimens. Specimens older than 48 hours.
New York State Clients:
Clotted, refrigerated, or frozen specimens. EDTA specimens older than 30 hours and heparin specimens older than 48 hours.


Stability (collection to initiation of testing): Ambient: 48 hours; Refrigerated: Unacceptable; Frozen: Unacceptable
New York State Clients:
Ambient: EDTA specimens - 30 hours, Heparin specimens - 48 hours; Refrigerated: Unacceptable; Frozen: Unacceptable

Reference Interval:
Reports include age appropriate reference intervals and interpretation
Components Reference Interval
% IgD By report
% IgM By report
% Total Ig By report
% HLA-DR By report
% CD19 By report
% IgA By report
% IgG By report

Interpretive Data: The B-cell Immunodeficiency Profile measures circulating B-cells (CD19), their surface immunoglobulins (Total Ig, IgG, IgD, IgM, and IgA) and a common HLA class II antigen. The percentage of lymphocytes expressing CD19, various immunoglobulin fractions and HLA-DR may be altered in certain immunologic abnormalities. For example, HLA-DR is absent on B-cells in the bare lymphocyte syndrome (MHC Class II Deficiency).

Please refer to Statement A in the Compliance Statements section in the front of the Laboratory Test Directory.
CPT Code(s): 88184 First marker; 88185 x6 Each additional marker
Cross References: B-Cell Immunodeficiency Profile , Surface Immunoglobulin expression on B-cells. Total I
 
 

 

 

 
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