Reference Interval:
| Component
| Reference Interval
| | % CD11b
| 90-100
| | CD11b Density
| 50-200
| | % CD15
| 98-100
| | CD15 Density
| 55-183
| | % CD16
| 90-100
| | CD16 Density
| 40-240
| | % CD18
| 90-100
| | CD18 Density
| 60-190
|
|
| Interpretive Data: |
The Neutrophil Receptor Panel measures CD11b, CD15, CD16, and CD18 on neutrophils. CD11b is the receptor for the C3bi fragment of complement. CD15 is a ligand for E and P selectins. CD16 is the IgG Fc receptor. CD11b is an alpha subunit, and CD18 is the beta subunit of Mac-1, also known as CR3. All of these receptors are normally found on neutrophils. The percentage of patient neutrophils bearing these receptors is reported. In addition, the receptor surface density of each antigen is compared to normal neutrophils and expressed as a percent. Values outside of the reference interval may correlate with abnormal neutrophil function. For example, CD18 is decreased or absent in leukocyte adhesion deficiency (LAD) type I and CD15 is decreased or absent in LAD type II.
Please refer to Statement A in the Compliance Statements section in the front of the Laboratory Test Directory.
|
| CPT Code(s): |
88184 First marker; 88185 x3 Each additional marker
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