ARUP's Laboratory Test Directory

Estrone, by Tandem Mass Spectrometry : 0093249

Mnemonic: ESTRNE TMS

Ordering Recommendation: Rarely indicated. If serum estrone measurement is needed, preferred test is Estrogens, Fractionated by Tandem Mass Spectrometry (0093248).
Methodology: Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry
Performed: Sun-Sat
Reported: 1-4 days
Specimen Required: Collect: Serum separator tube, lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin).

Specimen Preparation: Separate serum or plasma from cells within 2 hours of collection. Transfer 0.5 mL serum or plasma an ARUP Standard Transport Tube. (Min 0.3 mL)

Storage/Transport Temperature: Refrigerated.

Stability (collection to initiation of testing): After separation from cells: Ambient: 48 hours; Refrigerated: 1 week; Frozen: 1 month
Reference Interval:
Reference Intervals for Estrone-Children
Tanner Stages:
I
II
III
IV and V 		Males
less than 7 pg/mL
less than 11 pg/mL
1-31 pg/mL
2-30 pg/mL 		Females
less than 27 pg/mL
1-39 pg/mL
8-117 pg/mL
4-109 pg/mL
Age Group
7-9
10-12
13-15
16-17 		Males
less than 7 pg/mL
less than 11 pg/mL
1-30 pg/mL
1-32 pg/mL 		Females
less than 20 pg/mL
1-40 pg/mL
8-105 pg/mL
4-133 pg/mL

Reference Intervals for Estrone-Adults
Females 18 Years and Older Males 18 Years and Older
Premenopausal:
Early Follicular: less than 150 pg/mL
Late Follicular: 100-250 pg/mL
Luteal: less than 200 pg/mL 		9-36 pg/mL
Postmenopausal: 3-32 pg/mL

Interpretive Data:

See Compliance Statement B: www.aruplab.com/CS
CPT Code(s): 82679
Cross References: Estrone (E1) (Estrone, by Tandem Mass Spectrometry)