ARUP's Laboratory Test Directory

Bile Acids, Fractionated and Total by LC-MS/MS : 0092610
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Additional Technical Information
  


Mnemonic: BILE ACIDS

Ordering Recommendation: Do not use to diagnose liver dysfunction. Use to screen for inborn errors of bile acid metabolism or monitor bile acid therapy.
Methodology: Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry
Performed: Tue, Thu, Sat
Reported: 1-6 days
Specimen Required: Patient Prep: Patient should fast for a minimum of eight hours prior to specimen collection.

Collect: Plain red or serum separator tube.

Specimen Preparation: After clot formation, centrifuge specimen and pour off serum into a transport tube. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.2 mL)

Storage/Transport Temperature: Refrigerated. Store specimen refrigerated or frozen.

Stability (collection to initiation of testing): Ambient: 8 hours; Refrigerated: 2 weeks; Frozen: 6 months

Reference Interval:
7 years and older:
Cholic acid (CA) 0-1.9 µmol/L
Chenodeoxycholic acid (CDC) 0-3.4 µmol/L
Deoxycholic acid (DCA) 0-2.5 µmol/L
Ursodeoxycholic acid (UDC) 0-1.0 µmol/L
Total 0-7.0 µmol/L
Interpretive Data:

See Compliance Statement B: www.aruplab.com/CS
Note: Reference intervals were derived using samples obtained after an overnight fast.
CPT Code(s): 83789
Cross References: Bile Salts (Bile Acids, Fractionated & Total by LC-MS/MS), Chenodeoxycholic Acid (Bile Acids, Fractionated & Total by LC-MS/MS), Cholic Acid (Bile Acids, Fractionated & Total by LC-MS/MS), Deoxycholic Acid (Bile Acids, Fractionated & Total by LC-MS/MS), Fractionated Bile Acids (Bile Acids, Fractionated & Total by LC-MS/MS), Ursodeoxycholic Acid (UDC) (Bile Acids, Fractionated & Total by LC-MS/MS)