ARUP's Laboratory Test Directory

Opiates - Confirmation/Quantitation - Serum or Plasma : 0092354

Mnemonic: OPIS SP

Methodology: Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Performed: Sun-Sat
Reported: 1-4 days
Specimen Required: Collect: Gray (sodium fluoride/potassium oxalate). Also acceptable: Plain red, green (sodium heparin), lavender (EDTA), or pink (K2EDTA).

Specimen Preparation: Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 4 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 2 mL)

Storage/Transport Temperature: Refrigerated.

Unacceptable Conditions: Separator tubes. Plasma or whole blood collected in lt. blue (sodium citrate). Specimens exposed to repeated freeze/thaw cycles.

Stability (collection to initiation of testing): After separation from cells: Ambient: 1 week; Refrigerated: 2 weeks; Frozen: 3 years
Interpretive Data: Methodology: Quantitative Liquid Chromatography-Tandem Mass Spectrometry

Drugs covered: codeine, morphine, 6-acetylmorphine, hydrocodone, hydromorphone, oxycodone and oxymorphone. All drugs covered are the non-glucuronidated (free) form.

Positive cutoff: 2 ng/mL

For medical purposes only; not valid for forensic use.

The absence of expected drug(s) and/or drug metabolite(s) may indicate non-compliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, or limitations of testing. The concentration value must be greater than or equal to the cutoff to be reported as positive. A very small amount of an unexpected drug analyte in the presence of a large amount of an expected drug analyte may reflect pharmaceutical impurity. Interpretive questions should be directed to the laboratory.

See Compliance Statement B: www.aruplab.com/CS
CPT Code(s): 83925
Cross References: Codeine (Drugs of Abuse Confirmation/Quantitation - Opiates - Serum or Plasma), Codeine and Metabolite (Drugs of Abuse Confirmation/Quantitation - Opiates - Serum or Plasma), Dilaudid (Drugs of Abuse Confirmation/Quantitation - Opiates - Serum or Plasma), Heroin (Drugs of Abuse Confirmation/Quantitation - Opiates - Serum or Plasma), Hydrocodone and Metabolite (Drugs of Abuse Confirmation/Quantitation - Opiates - Serum or Plasma) , Hydromorphone (Drugs of Abuse Confirmation/Quantitation - Opiates - Serum or Plasma) , Morphine (Drugs of Abuse Confirmation/Quantitation - Opiates - Serum or Plasma) , MS Contin (Drugs of Abuse Confirmation/Quantitation - Opiates - Serum or Plasma), Norco (Drugs of Abuse Confirmation/Quantitation - Opiates - Serum or Plasma), Opana (Drugs of Abuse Confirmation/Quantitation - Opiates - Serum or Plasma), Opiates Quantitation (Drugs of Abuse Confirmation/Quantitation - Opiates - Serum or Plasma), Oxycodone (Drugs of Abuse Confirmation/Quantitation - Opiates - Serum or Plasma), Oxycodone and Metabolite (Drugs of Abuse Confirmation/Quantitation - Opiates - Serum or Plasma) , OxyContin (Drugs of Abuse Confirmation/Quantitation - Opiates - Serum or Plasma), Oxymorphone (Drugs of Abuse Confirmation/Quantitation - Opiates - Serum or Plasma) , Pain Management (Drugs of Abuse Confirmation/Quantitation - Opiates - Serum or Plasma), Percocet (Drugs of Abuse Confirmation/Quantitation - Opiates - Serum or Plasma), Percodan (Drugs of Abuse Confirmation/Quantitation - Opiates - Serum or Plasma), Roxicet (Drugs of Abuse Confirmation/Quantitation - Opiates - Serum or Plasma), Roxiprin (Drugs of Abuse Confirmation/Quantitation - Opiates - Serum or Plasma), Tylox (Drugs of Abuse Confirmation/Quantitation - Opiates - Serum or Plasma)