ARUP's Laboratory Test Directory
| 0092305: Francisella tularensis Antibodies, Total |
| Test Mnemonic: FRAN TULAR | |
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Methodology: Agglutination
Performed: Mon-Fri Reported: 2-5 days |
| Specimen Required: | |
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Collect: One 4 mL SST.
Transport: 1 mL serum at 2-8°C. (Min: 0.3 mL) Submit specimen in an ARUP Standard Transport Tube. Pediatric Collection/Transport: 0.15 mL serum at 2-8°C. Remarks: Remove serum from cells ASAP. Unacceptable Conditions: Heat inactivated, lipemic, turbid, or contaminated specimens. Stability: After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year |
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| Reference Interval: |
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Less than 1:20 - Negative 1:20 to 1:80 - Equivocal Greater than or equal to 1:160 - Positive |
| Interpretive Data: | |
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In the presence of compatible symptoms, a Francisella tularensis antibody titer of 1:160 or greater in an acute specimen supports a presumptive diagnosis of tularemia. However, a titer greater than or equal to 1:160 may also reflect past infection. An equivocal titer may be due to crossreactive antibodies (Brucella, Yersinia, or Rickettsia), past infection, or very recent infection. A four-fold rise in titer between acute and convalescent sera is required for definitive serologic diagnosis of tularemia.
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| CPT Code(s): | |
| 86000 |