ARUP's Laboratory Test Directory

Francisella tularensis Antibodies, Total : 0092305

Mnemonic: FRAN TULAR

Methodology: Agglutination
Performed: Mon-Fri
Reported: 2-5 days
Specimen Required: Collect:  One 4 mL serum separator tube.

Transport:  1 mL serum at 2-8°C. (Min: 0.3 mL) Submit specimen in an ARUP Standard Transport Tube.

Pediatric Collection/Transport:  0.15 mL serum at 2-8°C.

Remarks:  Remove serum from cells ASAP.

Unacceptable Conditions:  Heat inactivated, lipemic, turbid, or contaminated specimens.

Stability:  After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year
Reference Interval:
Less than 1:20 - Negative
1:20 to 1:80 - Equivocal
Greater than or equal to 1:160 - Positive
Interpretive Data: In the presence of compatible symptoms, a Francisella tularensis antibody titer of 1:160 or greater in an acute specimen supports a presumptive diagnosis of tularemia. However, a titer greater than or equal to 1:160 may also reflect past infection. An equivocal titer may be due to crossreactive antibodies (Brucella, Yersinia, or Rickettsia), past infection, or very recent infection. A four-fold rise in titer between acute and convalescent sera is required for definitive serologic diagnosis of tularemia.
CPT Code(s): 86668
 
 

 

 

 
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