ARUP's Laboratory Test Directory

Everolimus (Certican) : 0092118

Mnemonic: EVEROLIMUS

Methodology: Tandem Mass Spectrometry
Performed: Sun-Sat
Reported: Within 24 hours
Specimen Required: Collect:  One 3 mL lavender (EDTA) or pink (K2EDTA).

Transport:  3 mL whole blood at 2-8°C.  (Min: 1 mL)

Pediatric Collection/Transport:  0.5 mL whole blood at 2-8°C.

Unacceptable Conditions:  Serum, plasma, and specimens ambient longer than 24 hours.

Stability:  Ambient: 24 hours; Refrigerated: 2 weeks; Frozen: 2 weeks
Reference Interval:
Therapeutic Range: By report
Interpretive Data: The therapeutic and toxic ranges for everolimus are not well defined, and will likely depend on coadministered medications, the organ transplanted, time post-transplant, and other aspects of the specific clinical application.  For example, a Cmin target range of 7.8-15 ng/mL has been suggested for everolimus administered with cyclosporine, in the early post renal transplant period.
CPT Code(s): 80299
 
 

 

 

 
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