ARUP's Laboratory Test Directory

Everolimus : 0092118

Mnemonic: EVEROLIMUS

Methodology: Tandem Mass Spectrometry
Performed: Sun-Sat
Reported: Within 24 hours
Specimen Required: Collect:  One 3 mL lavender (EDTA) or pink (K2EDTA).

Storage/Transport Temperature:  3 mL whole blood at 2-8°C.  (Min: 0.25 mL)

Unacceptable Conditions:  Serum, plasma, and specimens ambient longer than 24 hours. Clotted specimens.

Stability (collection to initiation of testing):  Ambient: 24 hours; Refrigerated: 2 weeks; Frozen: 2 weeks
Reference Interval:
3-8 ng/mL
Interpretive Data: The suggested therapeutic range is based on a trough specimen and is intended for kidney transplant patients receiving everolimus in combination with cyclosporine. The optimal therapeutic range for a given patient may differ from this suggested range based on treatment phase (initiation or maintenance), use in combination with other drugs, time of specimen collection relative to prior dose, type of transplanted organ and/or the therapeutic approach of the transplant center. Symptoms of toxicity are more likely at trough concentrations that exceed 12 ng/mL.
CPT Code(s): 80299
Cross References: Certican™
 
 

 

 

 
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