ARUP's Laboratory Test Directory

Paraneoplastic Pemphigus Antibody Screen : 0092107

Mnemonic: PARA PEMPH

Methodology: Indirect Fluorescent Antibody
Performed: Varies
Reported: 3-7 days
Specimen Required: Collect: Plain red or serum separator tube.

Specimen Preparation: Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature: Room temperature.

Remarks: For specimens less than 0.5 mL, call the Immunodermatology lab at (866) 266-5699.

Unacceptable Conditions: Hemolyzed or lipemic specimens.

Stability (collection to initiation of testing): Ambient: 4 days; Refrigerated: 3 months; Frozen: Indefinitely

Reference Interval:
By report
Note: The methodology is indirect immunofluorescence (IFA) of patient serum on substrates from rodents including mouse heart, liver, bladder and rat bladder to detect characteristic staining: intercalated discs in heart; portal tracts in liver; and simple columnar epithelium cell surface and basement membrane zone in bladders.

Characteristic staining of two or more substrate tissues is required for diagnosis.  Staining must include bladder epithelial cell surface staining.
CPT Code(s): 88347 x4