ARUP's Laboratory Test Directory

0091363: Drugs of Abuse Confirmation/Quantitation - Propoxyphene & Metabolite - Serum or Plasma

Test Mnemonic: PROPOXY SP
Methodology: Liquid Chromatography-Tandem Mass Spectrometry

Performed: Sun-Sat

Reported: 1-4 days

Specimen Required:  
Collect: Two 7 mL gray (sodium fluoride/potassium oxalate).  Also acceptable: plain red, green (sodium heparin), lavender (EDTA), or pink (K2EDTA).

Transport: 4 mL serum or plasma at 20-25°C. (Min: 2.5 mL)  Submit specimen in an ARUP Standard Transport Tube.

Pediatric Collection/Transport: 1.5 mL serum or plasma at 20-25°C.

Unacceptable Conditions: Specimens exposed to repeated freeze/thaw cycles. Serum separator tubes and plasma or whole blood from lt. blue tubes (sodium citrate).

Stability: After separation from cells: Ambient: 1 week; Refrigerated: 2 weeks; Frozen: Frozen: 3 years

Reference Interval:
By report

Interpretive Data:
For medical purposes only; not valid for forensic use.

Drugs covered: propoxyphene and metabolite (norpropoxyphene - qualitative only).

Positive cutoff: 10 ng/mL
Average serum concentrations on a daily regimen of 65 mg, three times a day, drawn 2 hours after last dosage: propoxyphene 420 ng/mL; norpropoxyphene (25-50% analgesic activity) 1450 ng/mL.



CPT Code(s):
80299