ARUP's Laboratory Test Directory

Drugs of Abuse Confirmation/Quantitation - Propoxyphene & Metabolite - Serum or Plasma : 0091363

Mnemonic: PROPOXY SP

Methodology: Liquid Chromatography-Tandem Mass Spectrometry
Performed: Sun-Sat
Reported: 1-4 days
Specimen Required: Collect:  Two 7 mL gray (sodium fluoride/potassium oxalate).  Also acceptable: plain red, green (sodium heparin), lavender (EDTA), or pink (K2EDTA).

Transport:  4 mL serum or plasma at 20-25°C. (Min: 2.5 mL)  Submit specimen in an ARUP Standard Transport Tube.

Pediatric Collection/Transport:  1.5 mL serum or plasma at 20-25°C.

Unacceptable Conditions:  Specimens exposed to repeated freeze/thaw cycles. Serum separator tubes and plasma or whole blood from lt. blue tubes (sodium citrate).

Stability:  After separation from cells: Ambient: 1 week; Refrigerated: 2 weeks; Frozen: Frozen: 3 years
Reference Interval:
By report
Interpretive Data: For medical purposes only; not valid for forensic use.

Drugs covered:
propoxyphene and metabolite (norpropoxyphene - qualitative only).

Positive cutoff:
10 ng/mL
Average serum concentrations on a daily regimen of 65 mg, three times a day, drawn 2 hours after last dosage: propoxyphene 420 ng/mL; norpropoxyphene (25-50% analgesic activity) 1450 ng/mL.
CPT Code(s): 80299
 
 

 

 

 
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