ARUP's Laboratory Test Directory

Chlorpromazine : 0090870

Mnemonic: CHLORP

Methodology: Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Performed: Mon, Thu
Reported: 1-5 days
Specimen Required: Patient Prep: Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.

Collect: Plain red. Also acceptable: Lavender (K2 or K3EDTA) or pink (K2EDTA).

Specimen Preparation: Separate serum or plasma from cells within 2 hours of collection. Transfer 2 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 1 mL)
SST or PST: Separate serum or plasma from gel within 6 hours and hold at room temperature or separate within 2 hours and store refrigerated.

Storage/Transport Temperature: Refrigerated.

Unacceptable Conditions: Whole blood. Light blue (citrate) or yellow (SPS or ACD solution).

Stability (collection to initiation of testing): After separation from cells: Ambient: 12 hours; Refrigerated: 72 hours; Frozen: 5 days
Reference Interval:
Effective February 19, 2013
 
 Child (0 - 11 years) Adult (12 years and older)
Therapeutic Range 30-80 ng/mL 50-300 ng/mL
Toxic Level Greater than 200 ng/mL Greater than 750 ng/mL

Interpretive Data: Toxic concentrations may cause drowsiness, coma, hypotension, tachycardia and seizures. Large daily doses of chlorpromazine may cause phenothiazine sudden death syndrome.
CPT Code(s): 84022
Cross References: Largactil (Chlorpromazine), Ormazine (Chlorpromazine), Thorazine (Chlorpromazine), Thorazine Spansule (Chlorpromazine)