ARUP's Laboratory Test Directory
| 0090615: Carbamazepine, Free & Total |
| Test Mnemonic: FCARB | |
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Methodology: Immunoassay
Performed: Mon-Fri Reported: 1-4 days |
| Specimen Required: | |
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Collect: One 7 mL plain red. (Min: 3 mL)
Transport: 2 mL serum at 2-8°C. (Min: 1 mL) Submit specimen in an ARUP Standard Transport Tube. Pediatric Collection/Transport: 1 mL serum at 2-8°C. Remarks: Separate serum from cells ASAP. Unacceptable Conditions: EDTA plasma. Separator tubes. Stability: After separation from cells: Ambient: 5 days; Refrigerated: 5 days; Frozen: 4 months |
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| Reference Interval: | ||||||||||||
Therapeutic Range:
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| Interpretive Data: | |
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Free carbamazepine may be important to monitor in patients with altered or unpredictable protein binding capacity. Carbamazepine is also subject to drug-drug interactions due to displacement of protein binding and extensive metabolism. Cross-reactivity with metabolites may account for differences in carbamazepine among analytical methods. Calculating percent free attempts to minimize differences in assay cross-reactivity and may be useful in dose optimization.
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| CPT Code(s): | |
| 80156 Carbamazepine, total; 80157 Carbamazepine, free |