| Methodology: |
Chemiluminescent Immunoassay/Enzyme-Linked Immunosorbent Assay
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| Performed: |
Mon-Sat
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| Reported: |
4-7 days
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| Specimen Required: |
Collect: One 7 mL serum separator tube or plain red. Specimen must be drawn between 15 weeks, 0 days and 22 weeks, 6 days gestation.
Transport: 3 mL serum at 2-8°C. (Min: 1 mL) Submit specimen in an ARUP Standard Transport Tube.
Remarks: Requires a previously submitted first trimester specimen, Maternal Screening, Sequential, Specimen #1 (0081293).
This test requires a nuchal translucency (NT) measurement that has been performed by a certified ultrasonographer. The ultrasonographer MUST be certified to perform NT measurements by one of the following agencies: FASTER trial, Fetal Medicine Foundation (FMF) or Nuchal Translucency Quality Review (NTQR). To avoid possible test delays for an ultrasonographer that is new to our database, please contact the genetic counselor at 800-242-2787 x2020 prior to sending specimen.
The sequential maternal screen also requires the following information: a crown-rump length measurement (cm), ultrasonographer's name and certification number, date of ultrasound, patient's date of birth, current weight, due date, number of fetuses present, patient's race, if the patient requires insulin, if there is a known family history of neural tube defects, if the patient has had a previous pregnancy with a chromosome abnormality, if the patient is taking valproic acid or carbamazepine (Tegretol®), physician's name and phone number, and for in vitro fertilization pregnancies, the age of the egg donor. Separate serum from cells ASAP.
Unacceptable Conditions: Specimens exposed to repeated freeze/thaw cycles. Specimens collected in Heparin, EDTA, or citrate plasma. Hemolyzed specimens.
Stability: After separation from cells: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 1 year
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