ARUP's Laboratory Test Directory

0081208: Alpha Fetoprotein, Total & L3 Percent

Test Mnemonic: AFP L3
Methodology: Liquid-Phase Binding Immunoassay

Performed: Thu

Reported: 1-8 days

Specimen Required:  
Collect: One 3 mL red or SST.

Transport: 1 mL serum at 2-8°C.  Submit specimen in an ARUP Standard Transport Tube.

Pediatric Collection/Transport: 0.5 mL serum at 2-8°C.

Remarks: Separate serum from cells ASAP.  Avoid repeated freeze/thaw cycles.

Unacceptable Conditions: Plasma specimens.

Stability: After separation from cells: Ambient: 8 hours; Refrigerated: 1 week; Frozen: 3 months

Reference Interval:
 
Test Number Components Reference Interval
 Alpha Fetoprotein Total 0-15 ng/mL
 Alpha Fetoprotein L3 Percent Less than 10.0%

Interpretive Data:
The Wako LiBASys method is used. Results obtained with different assay methods or kits cannot be used interchangeably. The Wako AFP-L3% assay is intended as a risk assessment test for the development of hepatocellular carcinoma in patients with chronic liver diseases. Elevated AFP-L3% values have been shown to be associated with a seven-fold increase in the risk of developing hepatocellular carcinoma within the next 21 months. Patients with elevated serum AFP-L3% should be more intensely evaluated for evidence of hepatocellular carcinoma. The result is not interpretable as a tumor marker in pregnant females.



CPT Code(s):
82107

 

 

 
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