ARUP's Laboratory Test Directory

Alpha Fetoprotein, Total and L3 Percent : 0081208
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Additional Technical Information
  


Mnemonic: AFP L3

Methodology: Quantitative Liquid Chromatography/Immunoassay
Performed: Thu
Reported: 1-8 days
Specimen Required: Collect: Serum separator tube.

Specimen Preparation: Allow specimen to clot completely at room temperature. Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature: Frozen.

Unacceptable Conditions: Plasma.

Stability (collection to initiation of testing): After separation from cells: Ambient: 8 hours; Refrigerated: 5 days; Frozen: 3 months (avoid repeated freeze/thaw cycles)

Reference Interval:
By report
 
Test Number Components Reference Interval
 Alpha Fetoprotein Total 0-15 ng/mL
 Alpha Fetoprotein L3 Percent 0-9.9 percent

Interpretive Data: The µTASWako method is used. Results obtained with different assay methods or kits cannot be used interchangeably. The AFP L3 Percent assay is intended as a risk assessment for the development of hepatocellular carcinoma in patients with chronic liver diseases. Patients with elevated serum AFP-L3 percent should be more intensely evaluated for evidence of hepatocellular carcinoma since elevated values have been shown to be associated with a seven-fold increase in the risk for developing hepatocellular carcinoma within 21 months. For pregnant females, the result is not interpretable as a tumor marker.
CPT Code(s): 82107
Cross References: AFP (Liver Cancer) (Alpha Fetoprotein, Total and L3 Percent), AFP-L3% (Alpha Fetoprotein, Total and L3 Percent), Alpha Fetoprotein (Liver Cancer) (Alpha Fetoprotein, Total and L3 Percent), Alpha Fetoprotein, Total and L3 Percent (Alpha Fetoprotein, Total and L3 Percent), Alpha-Fetoprotein (AFP) L3% and Total, Hepatocellular Carcinoma Tumor Marker, Serum (Alpha Fetoprotein, Total and L3 Percent) , Hepatocellular Carcinoma AFP (Alpha Fetoprotein, Total and L3 Percent)