| Methodology: |
Chemiluminescent Immunoassay/Enzyme-Linked Immunosorbent Assay
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| Performed: |
Mon, Wed, Fri
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| Reported: |
2-4 days
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| Specimen Required: |
Collect: One 7 mL serum separator tube or plain red. Specimen must be drawn in the first trimester between 11 weeks, 0 days and 13 weeks, 6 days. (Crown-Rump length (CRL) must be between 4.2-7.9 cm).
Transport: 3 mL serum at 2-8°C. (Min: 1 mL) Submit specimen in an ARUP Standard Transport Tube.
Remarks: This test requires a nuchal translucency (NT) measurement that has been performed by a certified ultrasonographer. The ultrasonographer MUST be certified to perform NT measurements by one of the following agencies: FASTER trial, Fetal Medicine Foundation (FMF) or Nuchal Translucency Quality Review (NTQR). To avoid possible test delays for an ultrasonographer that is new to our database, please contact the genetic counselor at 800-242-2787 x2020 prior to sending specimen.
If an NT is unobtainable, order Maternal Serum Integrated Screen (0081062 and 0081064), which can be interpreted without an NT value.
The First Trimester Maternal Screen also requires the following information: a crown-rump length measurement (cm), ultrasonographer's name and certification number, date of ultrasound, patient's date of birth, current weight, due date, number of fetuses present, patient's race, if the patient has had a previous pregnancy with a chromosome abnormality, physician's name and phone number; and for in vitro fertilization pregnancies, the age of the egg donor. Separate serum from cells ASAP.
Unacceptable Conditions: Specimens exposed to repeated freeze/thaw cycles. Hemolyzed specimens. Heparin, EDTA or citrated plasma. A crown-rump length greater than 7.9 cm.
Stability: After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 month
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