ARUP's Laboratory Test Directory

0081150: Maternal Serum Screen, First Trimester

[ image for: Patient History For Maternal Serum Testing]
Patient History For Maternal Serum Testing
  

Test Mnemonic: MS FT
Methodology: Chemiluminescent Immunoassay/Enzyme-Linked Immunosorbent Assay

Performed: Mon, Wed, Fri

Reported: 2-4 days

Specimen Required:  
Collect: One 7 mL SST or plain red. Specimen must be drawn in the first trimester between 11 weeks, 0 days and 13 weeks, 6 days. (Crown-Rump length (CRL) must be between 4.2-7.9 cm).

Transport: 3 mL serum at 2-8°C.  (Min: 1 mL)  Submit specimen in an ARUP Standard Transport Tube.

Remarks: This test requires a nuchal translucency (NT) measurement that has been performed by a certified ultrasonographer.  The ultrasonographer MUST be certified to perform NT measurements by one of the following agencies: FASTER trial, Fetal Medicine Foundation (FMF) or Nuchal Translucency Quality Review (NTQR).  To avoid possible test delays for an ultrasonographer that is new to our database, please contact the genetic counselor at 800-242-2787 x2020 prior to sending specimen.

If an NT is unobtainable, order Maternal Serum Integrated Screen (0081062 and 0081064), which can be interpreted without an NT value.

The First Trimester Maternal Screen also requires the following information: a crown-rump length measurement (cm), ultrasonographer's name and certification number, date of ultrasound, patient's date of birth, current weight, due date, number of fetuses present, patient's race, if the patient has had a previous pregnancy with a chromosome abnormality, physician's name and phone number; and for in vitro fertilization pregnancies, the age of the egg donor. Separate serum from cells ASAP.

Unacceptable Conditions: Specimens exposed to repeated freeze/thaw cycles.  Hemolyzed specimens. Heparin, EDTA or citrated plasma.  A crown-rump length greater than 7.9 cm.

Stability: After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 month

Reference Interval:
By report

Note:
This test does not screen for Open Neural Tube Defect (ONTD). This test is used to screen for fetal risk of Down syndrome (trisomy 21) and trisomy 18.

CPT Code(s):
84702 HCGMS; 84163 PAPP-A

 

 

 
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