ARUP's Laboratory Test Directory
| 0081064: Maternal Serum Screening, Integrated, Specimen #2 |
![[ image for: Maternal Serum Screen, Integrated Test Request Form Required]](icon_15.jpg){kind=icon} | Maternal Serum Screen, Integrated Test Request Form Required | ![[ image for: Patient History For Maternal Serum Testing]](icon_17.jpg){kind=icon} | Patient History For Maternal Serum Testing |
| Test Mnemonic: MS INT-2 | |
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Methodology: Chemiluminescent Immunoassay/Enzyme-Linked Immunosorbent Assay
Performed: Mon-Sat Reported: 4-7 days |
| Specimen Required: | |
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Collect: One 7 mL SST or plain red. Specimen must be drawn between 15 weeks, 0 days and 22 weeks, 6 days gestation.
Transport: 3 mL serum at 2-8°C. (Min: 1 mL) Submit specimen in an ARUP Standard Transport Tube. Remarks: Requires a previously submitted first trimester specimen, Maternal Serum Screening, Integrated, Specimen #1 (0081062). The final Integrated Maternal Screen can be interpreted with or without a nuchal translucency (NT) measurement. If performed, the NT measurement must be obtained between 10 weeks, 3 days and 13 weeks, 6 days gestation. The NT measurement must also be performed by an ultrasonographer that is certified by one of the following agencies: FASTER trial, Fetal Medicine Foundation (FMF) or Nuchal Translucency Quality Review (NTQR). To avoid possible test delays for an ultrasonographer that is new to our database, please contact the genetic counselor at 800-242-2787 x2020 prior to sending specimen. This test also requires the following information: a crown-rump length measurement (cm), ultrasonographer's name and certification number, date of ultrasound, patient's date of birth, current weight, due date, number of fetuses present, patient's race, if the patient requires insulin, if there is a known family history of neural tube defects, if the patient has had a previous pregnancy with a chromosome abnormality, if the patient is taking valproic acid or carbamazepine (Tegretol®), physician's name and phone number, and for in vitro fertilization pregnancies, the age of the egg donor. Separate serum from cells ASAP. Unacceptable Conditions: Specimens exposed to repeated freeze/thaw cycles. Heparin, EDTA, and citrate plasma. Hemolyzed specimens. Stability: After separation from cells: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 1 year |
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| Reference Interval: |
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By report: includes AFP, hCG, Estriol, Inhibin A, and previous PAPP-A. Intervals are based upon weeks of gestation. |
| Interpretive Data: | |
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Refer to report.
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| CPT Code(s): | |
| 82105 AFP; 84702 HCG; 82677 Estriol; 86336 Inhibin A |