ARUP's Laboratory Test Directory

Lipoprotein-Associated Phospholipase A2 (PLAC®) : 0081055

Mnemonic: PLAC

Ordering Recommendation: Not recommended for cardiovascular disease risk assessment in asymptomatic adults. May aid in CVD risk stratification in specific populations.
Methodology: Quantitative Enzyme-Linked Immunosorbent Assay
Performed: Sun, Wed, Fri
Reported: 1-4 days
Specimen Required: Collect: Green top tube (lithium or sodium heparin), plain red, or serum separator tube . Also acceptable: Lavender (EDTA) or pink (K2EDTA).

Specimen Preparation: Allow serum specimen to clot completely at room temperature. Centrifuge and separate serum or plasma from cells ASAP or within 2 hours of collection. Transport 1 mL serum or plasma. (Min: 0.2 mL)

Storage/Transport Temperature: Refrigerated.

Unacceptable Conditions: Whole blood.

Stability (collection to initiation of testing): After separation from cells: Ambient: 4 hours; Refrigerated: 1 week; Frozen: Unacceptable
Reference Interval:
0-234 ng/mL
Interpretive Data: Patients with high lipoprotein-associated phospholipase A2 concentrations greater than or equal to 235 ng/mL are at increased risk for cardiovascular events including myocardial infarction and ischemic stroke.  The median lipoprotein-associated phospholipase A2 value for a healthy population is 235 ng/mL.

This test is performed pursuant to an agreement with diaDexus, Inc.
CPT Code(s): 83698
Cross References: LpPLA, LpPLA2, PLA2, PLAC®