ARUP's Laboratory Test Directory
| 0080397: Serotonin, Serum |
| Test Mnemonic: SEROT-SER | |
|
Methodology: High Performance Liquid Chromatography
Performed: Sun, Wed, Fri Reported: 1-5 days |
| Specimen Required: | |
|
Collect: One 4 mL SST.
Transport: 1 mL serum, frozen. (Min: 0.6 mL) Submit specimen in an ARUP Standard Transport Tube. Pediatric Collection/Transport: 0.5 mL serum, frozen. Submit sample in an ARUP Standard Transport Tube. Remarks: CRITICAL FROZEN. Separate samples must be submitted when multiple tests are ordered. In general, EDTA whole blood (as compared to serum) preserved with ascorbic acid will give values most representative of blood concentrations. Most (95%) of blood serotonin is found in platelets - refer to Serotonin, Whole Blood (0080395). Unacceptable Conditions: Nonfrozen samples. Stability: After separation from cells: Ambient: Unacceptable; Refrigerated: 24 hours; Frozen: 1 month |
|
| Reference Interval: |
| 50-220 ng/mL |
| Note: | |
| Medications that may affect serotonin concentrations include lithium, MAO inhibitors, methyldopa, morphine, and reserpine. In general, foods that contain serotonin do not interfere significantly. Slight increases may be seen in acute intestinal obstruction, acute MI, cystic fibrosis, dumping syndromes, and nontropical sprue. Metastasizing abdominal carcinoid tumors often show serotonin concentrations greater than 400 ng/mL. |
| CPT Code(s): | |
| 84260 |