ARUP's Laboratory Test Directory
| 0080395: Serotonin, Whole Blood |
| Test Mnemonic: SEROT-WB | |
|
Methodology: High Performance Liquid Chromatography
Performed: Sun, Wed, Fri Reported: 1-5 days |
| Specimen Required: | |
|
Collect: One 3 mL lavender (EDTA) or pink (K2EDTA). Place on ice. Transfer whole blood into an ARUP Serotonin Transport Tube containing ascorbic acid (available through ARUP Client Services - ARUP Supply #16568). Mix Well. Specimen must be preserved and frozen within 2 hours of collection.
Transport: 3 mL whole blood in an ARUP Serotonin Transport Tube, frozen. (Min: 1 mL) Pediatric Collection/Transport: Serotonin, Serum (0080397) is recommended for pediatric patients. Remarks: CRITICAL FROZEN. Separate samples must be submitted when multiple tests are ordered. Unacceptable Conditions: Nonfrozen samples. Stability: After transfer to Serotonin Transport Tube: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 1 month |
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| Reference Interval: |
| 50-200 ng/mL |
| Note: | |
| Medications that may affect serotonin concentrations include lithium, MAO inhibitors, methyldopa, morphine, and reserpine. In general, foods that contain serotonin do not interfere significantly. Slight increases may be seen in acute intestinal obstruction, acute MI, cystic fibrosis, dumping syndromes, and nontropical sprue. Metastasizing abdominal carcinoid tumors often show serotonin concentrations greater than 400 ng/mL. |
| CPT Code(s): | |
| 84260 |