ARUP's Laboratory Test Directory

Cancer Antigen 27.29 : 0080392

Mnemonic: CA27.29

Methodology: Quantitative Chemiluminescent Immunoassay
Performed: Sun-Sat
Reported: Within 24 hours
Specimen Required: Collect: Plain red or serum separator tube.

Specimen Preparation: Allow specimen to clot completely at room temperature. Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature: Frozen.

Unacceptable Conditions: Plasma.

Stability (collection to initiation of testing): After separation from cells: Ambient: 8 hours; Refrigerated: 48 hours; Frozen: 3 months
Reference Interval:
0-40 U/mL
Interpretive Data: Test Information: The CA 27.29 assay is intended for use in monitoring: 1) disease progression and/or response to therapy in patients with metastatic disease, and 2) disease recurrence in patients treated previously for stages II or III breast carcinoma who are clinically free of the disease. Serial testing in patients who are clinically free of disease should be used in conjunction with other clinical methods for early detection of cancer recurrence.

Limitations: Patients with confirmed breast carcinoma frequently have CA 27.29 assay values in the same range as healthy individuals.  Elevations may also be observed in patients with non-malignant disease. Results of this test must always be interpreted in the context of morphologic and other relevant data and should not be used alone for a diagnosis of malignancy.

Methodology: Siemens Advia Centaur CA 27.29 chemiluminescent immunoassay was used. Results obtained with different assay methods or kits cannot be used interchangeably.
CPT Code(s): 86300
Cross References: CA 27.29 (Cancer Antigen 27.29)