ARUP's Laboratory Test Directory

Pyridinoline & Deoxypyridinoline by HPLC : 0080342

Mnemonic: PYD & DPD

Methodology: High Performance Liquid Chromatography
Performed: Wed
Reported: 6-14 days
Specimen Required: Collect:  Urine.  First morning void.

Transport:  9 mL urine, frozen. (Min: 4.5 mL) Submit specimen in two ARUP Standard Transport Tubes.

Pediatric Collection/Transport:  4.5 mL urine, frozen.

Remarks:  Ship frozen in two ARUP Standard Transport Tubes.

Unacceptable Conditions:  Random urine.

Stability:  Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 6 months
Reference Interval:
 
   

Age 		PYR
µmol/mol creatinine 		DPYR
µmol/mol creatinine
DPYR/PYR Ratio
0-11 months 353-560 µmol/mol crt 46-113 µmol/mol crt 0.13-0.20
1-3 years 108-400 µmol/mol crt 19-94 µmol/mol crt 0.18-0.24
4-9 years 117-325 µmol/mol crt 20-75 µmol/mol crt 0.19-0.25
10-14 years 81-267 µmol/mol crt 13-61 µmol/mol crt 0.17-0.27
15-19 years 38-80 µmol/mol crt 10-18 µmol/mol crt 0.20-0.26
20 years and older 20-40 µmol/mol crt 5-11 µmol/mol crt 0.23-0.29

Interpretive Data: Pyridinoline and Deoxypyridinoline excretion follows a circadian rhythm.  Reference intervals have been established on first morning void urine samples.
CPT Code(s): 82523
 
 

 

 

 
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