ARUP's Laboratory Test Directory

0080342: Pyridinoline & Deoxypyridinoline by HPLC

Test Mnemonic: PYD & DPD
Methodology: High Performance Liquid Chromatography

Performed: Wed

Reported: 6-14 days

Specimen Required:  
Collect: Urine.  First morning void.

Transport: 9 mL urine, frozen. (Min: 4.5 mL) Submit specimen in two ARUP Standard Transport Tubes.

Pediatric Collection/Transport: 4.5 mL urine, frozen.

Remarks: Ship frozen in two ARUP Standard Transport Tubes.

Unacceptable Conditions: Random urine.

Stability: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 6 months

Reference Interval:
 
   

Age
PYR
µmol/mol creatinine
DPYR
µmol/mol creatinine

DPYR/PYR Ratio
0-11 months 353-560 µmol/mol crt 46-113 µmol/mol crt 0.13-0.20
1-3 years 108-400 µmol/mol crt 19-94 µmol/mol crt 0.18-0.24
4-9 years 117-325 µmol/mol crt 20-75 µmol/mol crt 0.19-0.25
10-14 years 81-267 µmol/mol crt 13-61 µmol/mol crt 0.17-0.27
15-19 years 38-80 µmol/mol crt 10-18 µmol/mol crt 0.20-0.26
20 years and older 20-40 µmol/mol crt 5-11 µmol/mol crt 0.23-0.29

Interpretive Data:
Pyridinoline and Deoxypyridinoline excretion follows a circadian rhythm.  Reference intervals have been established on first morning void urine samples.



CPT Code(s):
82523

 

 

 
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