Ordering Recommendation

Preferred initial screening test for pyruvate kinase deficiency.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Lavender (EDTA) or Pink (K2EDTA). Also acceptable: Green (Sodium or Lithium Heparin) or Yellow (ACD Solution A or B).

Specimen Preparation

Do not freeze. Transport 1 mL whole blood. (Min: 0.5 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions
Remarks
Stability

Ambient: Unacceptable; Refrigerated: 20 days; Frozen: Unacceptable

Methodology

Quantitative Enzymatic Assay

Performed

Sun-Sat

Reported

1-2 days

Reference Interval

4.6-11.2 U/g Hb

Interpretive Data



Compliance Category

Standard

Note

Patients who have recently received transfusions have normal donor cells that may mask PK deficient erythrocytes.

Hotline History

N/A

CPT Codes

84220

Components

Component Test Code* Component Chart Name LOINC
0080290 Pyruvate Kinase 32552-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • PK
  • Pyruvate Kinase (RBC)
Pyruvate Kinase