ARUP's Laboratory Test Directory
| 0080269: Maternal Serum Screen, Alpha Fetoprotein, hCG, Estriol, & Inhibin A |
| Patient History For Maternal Serum Testing |   |   |
| Test Mnemonic: AFP MS4 | |
|
#ExistMethodology>
Methodology: Chemiluminescent Immunoassay
*ExistMethodology> #ExistPerformed> Performed: Sun-Sat *ExistPerformed> #ExistReported> Reported: 2-3 days *ExistReported> |
| Specimen Required: | |
|
#ExistCollect>
Collect: One 7 mL SST or plain red. Specimen must be drawn between 14 weeks, 0 days and 24 weeks, 6 days gestation.
*ExistCollect> #ExistTransport> Transport: 3 mL serum, frozen. (Min: 1 mL) Submit specimen in an ARUP Standard Transport Tube. *ExistTransport> #ExistRemarks> Remarks: The following information is required and must accompany the sample for test interpretation: patient's date of birth, current weight, due date, dating method (US, LMP), number of fetuses present, patient's race, if the patient requires insulin, if there is a known family history of neural tube defects, if the patient has had a previous pregnancy with a chromosome abnormality, if the patient is taking valproic acid or carbamazepine (Tegretol®), physician's name and phone number; and for in vitro fertilization pregnancies, the age of the egg donor. Separate serum from cells ASAP. *ExistRemarks> #ExistConditions> Unacceptable Conditions: Specimens exposed to repeated freeze/thaw cycles. Hemolyzed specimens. Heparin, EDTA, and citrate plasma. *ExistConditions> #ExistStability> Stability: After separation from cells: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 1 year *ExistStability> |
|
| Reference Interval: |
|
#ExistRefRange> By report: includes AFP, hCG, Estriol, and Inhibin A. Intervals are based upon weeks of gestation. *ExistRefRange> |
| Note: | |
| This test is used to screen for fetal risk of Down syndrome (trisomy 21), trisomy 18, and Open Neural Tube Defect (ONTD, spina bifida). |
| CPT Code(s): | |
| 82105 AFP; 84702 hCG; 82677 Estriol; 86336 Inhibin A |