Maternal Serum Screen, Alpha Fetoprotein, hCG, Estriol, & Inhibin A : ARUP Lab Tests

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Maternal Serum Screen, Alpha Fetoprotein, hCG, Estriol, & Inhibin A : 0080269

Patient History For Maternal Serum Testing

Mnemonic: AFP MS4

Methodology:	Quantitative Chemiluminescent Immunoassay
Performed:	Sun-Sat
Reported:	2-3 days
Specimen Required:	Patient Prep: Specimen must be drawn between 14 weeks, 0 days and 24 weeks, 6 days gestation. Collect: Serum separator tube or plain red. Specimen Preparation: Separate serum from cells ASAP or within 2 hours of collection. Transfer 3 mL serum to an ARUP Standard Transport Tube. (Min: 1 mL) Storage/Transport Temperature: Refrigerated. Remarks: The following information is required and must accompany the sample for test interpretation: patient's date of birth, current weight, due date, dating method (US, LMP), number of fetuses present, patient's race, if the patient requires insulin, if there is a known family history of neural tube defects, if the patient has had a previous pregnancy with a chromosome abnormality, if the patient is taking valproic acid or carbamazepine (Tegretol®), physician's name and phone number; and for in vitro fertilization pregnancies, the age of the egg donor. Unacceptable Conditions: Heparin, EDTA, or citrate plasma. Specimens exposed to repeated freeze/thaw cycles. Hemolyzed specimens. Stability (collection to initiation of testing): After separation from cells: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 1 year

Reference Interval: By report Includes AFP, hCG, Estriol, and Inhibin A. Intervals are based upon weeks of gestation.
Note:	This test is used to screen for fetal risk of Down syndrome (trisomy 21), trisomy 18, and Open Neural Tube Defect (ONTD, spina bifida).
CPT Code(s):	82105 AFP; 84702 hCG; 82677 Estriol; 86336 Inhibin A
Cross References:	AFP MS4 (Quad) (Maternal Serum Screen, Alpha Fetoprotein, hCG, Estriol, & Inhibin A), Alpha Fetoprotein, hCG, Estriol, & Inhibin (Maternal Serum Screen, Alpha Fetoprotein, hCG, Estriol, & Inhibin A) , Quad AFP (Maternal Serum Screen, Alpha Fetoprotein, hCG, Estriol, & Inhibin A)

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