ARUP's Laboratory Test Directory

Prostate Specific Antigen, Total with Reflex to Free PSA (Includes Free Percentage) : 0080264

Mnemonic: TPSAR

Ordering Recommendation: Do not use for initial prostate cancer screening; preferred test is total prostate specific (PSA) antigen (0070121) in conjunction with digital rectal exam (DRE). May be useful in distinguishing cancer from benign conditions in patients with mildly elevated total PSA and negative DRE.
Methodology: Quantitative Electrochemiluminescent Immunoassay
Performed: Sun-Sat
Reported: Within 24 hours
Specimen Required: Collect: Plasma separator tube or serum separator tube. Also acceptable: Plain red, green (sodium or lithium heparin), lavender (EDTA), or pink (K2EDTA).

Specimen Preparation: Allow specimen to clot completely at room temperature. Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature: Frozen.

Unacceptable Conditions: Grossly hemolyzed specimens. Vaginal washings.

Stability (collection to initiation of testing): After separation from cells: Ambient: 8 hours; Refrigerated: 48 hours; Frozen: 3 months

Reference Interval:
Refer to report.
 
Test Number Components Reference Interval
 Prostate Specific Antigen, Total 0.0-4.0 ng/mL
 Prostate Specific Antigen, Free By report
 Prostate Specific Antigen Percent Free By report

Note: If PSA Total is between 3.0-10.0 ng/mL, then Free PSA testing will be added. Additional charges apply.

The Free PSA percentage is calculated using results of the Total and Free PSA tests.
CPT Code(s): 84153; if reflexed, add 84154
Cross References: Free Ratio Reflex (Prostate Specific Antigen, Total with Reflex to Free PSA (Includes Free Percentage) , PSA Total (Prostate Specific Antigen, Total w/ Rflx to Free PSA (Includes Free Percentage))