ARUP's Laboratory Test Directory

0080044: Amino Acids Quantitative, Urine

[ image for: Patient History For Biochemical Genetics]
Patient History For Biochemical Genetics
  

Test Mnemonic: UAA QNT
Methodology: Ion Exchange Chromatography

Performed: Mon-Fri

Reported: 3-7 days

Specimen Required:  
Collect: Random urine.  First-morning urine is preferred.

Transport: 10 mL aliquot from a well-mixed random urine, frozen. (Min: 2 mL) Submit specimen in an ARUP Standard Transport Tube. 

Pediatric Collection/Transport: 3 mL aliquot from a well-mixed random urine, frozen.

Remarks: CRITICAL FROZEN.  Separate specimens must be submitted when multiple tests are ordered.  As soon as possible after urine has been obtained, mix the collection well and freeze. Avoid dilute urine when possible. Clinical information is needed for appropriate interpretation.  Additional required information includes age, gender, diet (e.g., TPN therapy), drug therapy, and family history.  Biochemical Genetics Patient History Form is available on the ARUP Web site or by contacting ARUP Client Services.

Stability: Ambient: Unacceptable; Refrigerated: 24 hours; Frozen: 1 month

Reference Interval:
 
 
 0-5 months
µmol/g creatinine 		6-11 months
µmol/g creatinine 		1-3 years
µmol/g creatinine 		4-12 years
µmol/g creatinine 		13 years and older
µmol/g creatinine
Alanine 637-2159 319-1434 292-1151 151-814 142-602
Arginine 0-124 0-97 0-80 0-62 0-44
Asparagine 0-743 0-319 0-283 0-257 0-204
Aspartate 18-142 27-106 18-89 9-89 18-62
Citrulline 0-97 0-71 0-62 0-44 0-35
Cystine 62-345 53-133 53-186 35-106 27-151
Glutamine 460-2027 655-1744 398-2089 177-1177 177-673
Glutamic Acid 0-266 0-159 0-97 0-80 0-106
Glycine 1859-9709 1009-3938 974-3151 566-2177 381-1531
Histidine 638-3027 814-2460 602-2540 381-1912 230-1354
Homocystine Not Detected Not Detected Not Detected Not Detected Not Detected
Hydroxyproline 0-2832 0-195 0-115 0-115 0-115
Isoleucine 0-53 0-53 0-53 0-53 0-35
Leucine 27-221 35-142 27-159 27-142 27-97
Lysine 133-1761 115-699 89-611 89-602 62-513
Methionine 53-239 71-257 44-257 35-177 18-142
Ornithine 0-168 0-71 0-71 0-62 0-44
Phenylalanine 35-283 97-248 62-274 44-230 27-168
Proline 0-1885 0-124 0-80 0-80 0-80
Serine 372-2496 443-1213 283-1097 204-823 186-443
Taurine 53-2000 80-1089 106-1770 151-2036 142-1593
Threonine 151-1221 124-496 89-549 80-319 62-257
Tyrosine 53-487 97-478 89-425 53-310 27-204
Valine 27-230 53-168 0-71 27-151 27-115
Reference: Modified from Clinical Chemistry, vol 34, No 10, 1988 2092-2095

Note:
Common indications for urine amino acid testing include clinical situations such as: 1) acute life-threatening episode, 2) failure to thrive, 3) recurrent vomiting, 4) neurological deterioration, 5) hyperammonemia, 6) lethargy, 7) metabolic acidosis, 8) testing or following therapy for a specific inborn error of metabolism (PKU, MSUD, tyrosinemia, etc.), and 9) kidney stones.  Listing of clinical information is particularly important for appropriate interpretation.

CPT Code(s):
82139