ARUP's Laboratory Test Directory

Hemoglobin A1c : 0070426

Mnemonic: HBA1C

Ordering Recommendation: Use to diagnose and monitor diabetes mellitus. Monitor prediabetes.
Methodology: Quantitative High Performance Liquid Chromatography/Boronate Affinity
Performed: Sun-Sat
Reported: 1-2 days
Specimen Required: Collect: Lavender (EDTA) or pink (K2EDTA).

Specimen Preparation: Transport 5 mL whole blood in original tube. (Min: 1 mL)

Storage/Transport Temperature: Refrigerated.

Unacceptable Conditions: Tissue or urine.

Stability (collection to initiation of testing): Ambient: 24 hours; Refrigerated: 1 week; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval:
Effective May 21, 2012
 
Available Separately Components Reference Interval
No Hemoglobin A1c 4.0-5.6%
No Estimated Average Glucose By report

Interpretive Data: Hemoglobin A1c values of 5.7-6.4 percent indicate an increased risk for developing diabetes mellitus. Hemoglobin A1c values greater than or equal to 6.5 percent are diagnostic of diabetes mellitus. Diagnosis should be confirmed by repeating the Hb A1c test.

This boronate affinity Hb A1c method provides accurate analytical results in the presence of nearly all hemoglobin variants. Hb F higher than 10 percent of total Hb may yield falsely low results. Conditions that shorten red cell survival, such as the presence of unstable hemoglobins like Hb SS, Hb CC, and Hb SC, or other causes of hemolytic anemia may yield falsely low results. Iron deficiency anemia may yield falsely high results.
CPT Code(s): 83036
Cross References: A1C (Hemoglobin A1C) , Glycated Hemoglobin (Hemoglobin A1C) , HbA1c (Hemoglobin A1C)