ARUP's Laboratory Test Directory

Topiramate : 0070390

Mnemonic: TOPIR

Methodology: Quantitative Enzyme Immunoassay
Performed: Sun-Sat
Reported: Within 24 hours
Specimen Required: Collect: Plain red. Also acceptable: Lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin).

Specimen Preparation: Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.3 mL)

Storage/Transport Temperature: Refrigerated.

Unacceptable Conditions: Serum or plasma separator tubes. Grossly hemolyzed specimens.

Stability (collection to initiation of testing): After separation from cells: Ambient: 6 weeks; Refrigerated: 6 weeks; Frozen: 6 weeks

Reference Interval:
Therapeutic range not well established.
Interpretive Data: The proposed therapeutic range for seizure control is 5-20 µg/mL.  Pharmacokinetics varies widely, particularly with co-medications, age, and/or compromised renal function. 
CPT Code(s): 80201
Cross References: Topamax (Topiramate)