ARUP's Laboratory Test Directory

0070390: Topiramate

Test Mnemonic: TOPIR
Methodology: Fluorescence Polarization Immunoassay

Performed: Mon-Fri

Reported: 1-4 days

Specimen Required:  
Collect: One 5 mL plain red.  Also acceptable: green (sodium heparin).

Transport: 1 mL serum or plasma at 2-8°C.  (Min: 0.4 mL)  Submit specimen in an ARUP Standard Transport Tube.

Pediatric Collection/Transport: 0.4 mL serum or plasma at 2-8°C.  

Remarks: Separate serum or plasma from cells ASAP. Avoid use of separator tubes and gels.

Stability: After separation from cells: Ambient: 6 weeks; Refrigerated: 6 weeks; Frozen: 6 weeks

Reference Interval:
Therapeutic range not well established.

Interpretive Data:
The proposed therapeutic range for seizure control is 5-20 µg/mL.  Pharmacokinetics varies widely, particularly with co-medications, age, and/or compromised renal function. 



CPT Code(s):
80201

 

 

 
All ARUP Sites:        www.aruplab.com     ·     www.arupconsult.com     ·     www.arup.utah.edu     ·     www.childx.org     ·     www.utahblood.org