ARUP's Laboratory Test Directory

Estriol, Serum : 0070051

Mnemonic: EST

Ordering Recommendation: Screening test for fetal aneuploidy in conjunction with other biomarkers and ultrasonography. Indicator of fetal well-being and placental function.
Methodology: Quantitative Chemiluminescent Immunoassay
Performed: Sun-Sat
Reported: 1-2 days
Specimen Required: Collect: Serum separator tube.

Specimen Preparation: Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.6 mL)

Storage/Transport Temperature: Refrigerated.

Remarks: Patient gestational age required.

Unacceptable Conditions: Plasma.

Stability (collection to initiation of testing): After separation from cells: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 1 month (avoid repeated freeze/thaw cycles)

Reference Interval:
Effective November 19, 2012
 
Based on gestational age:  
25 weeks 1.9 - 6.7 ng/mL
26 weeks 2.0 - 7.3 ng/mL
27 - 29 weeks 2.1 - 9.1 ng/mL
30 - 31 weeks 2.4 - 10.6 ng/mL
32 - 37 weeks 2.6 - 16.7 ng/mL
Nonpregnant Female Less than 0.08 ng/mL
Male Less than 0.16 ng/mL

CPT Code(s): 82677
Cross References: E3 with Estriol (Estriol, Serum)