ARUP's Laboratory Test Directory
| 0065999: Human Papillomavirus (HPV) DNA Probe, High Risk, Cervical Brush (Digene) |
| Test Mnemonic: HPV-HI | |
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Methodology: Nucleic Acid Probe
Performed: Sun-Sat Reported: 1-2 days |
| Specimen Required: | |
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Collect: and Transport: Cervical brush in HPV Digene Collection Kit (cervical brush and specimen transport medium) ARUP Supply #12578.
Transport: Cervical brush in HPV Digene Kit specimen transport media at 2-8°C. Transport each specimen vial in an individual sealed bag. Remarks: Vaginal specimens are not recommended due to limited clinical correlative data. Unacceptable Conditions: Swabs or specimens in any other transport media. Urethral swabs. For specimens in ThinPrep® Pap Test transport media, refer to test code 0060750; for specimens in SurePath® Pap specimen transport media, refer to test code 0060744. Samples other than cervical are not acceptable for children under age 12. Stability: Digene transport medium: Ambient: 2 weeks; Refrigerated: 3 weeks; Frozen: 3 months |
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| Reference Interval: | |||||||||
Negative
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| Interpretive Data: | |
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A high-risk HPV test detects HPV genotypes: 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59 and 68, which are associated with cervical cancer and its precursor lesions. However, cross-reactions with other genotypes may occur. Results should be correlated with cytologic/histologic findings. Sensitivity may be affected by cellularity of specimen.
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| Note: | |
| A negative result does not rule out the presence of an HPV genotype absent from the test panel, a low level infection, or specimen sampling error. |
| CPT Code(s): | |
| 87621 |