ARUP's Laboratory Test Directory

Human Papillomavirus (HPV) DNA Probe, High Risk, Cervical Brush (Digene) : 0065999

Mnemonic: HPV-HI

Methodology: Nucleic Acid Probe
Performed: Sun-Sat
Reported: 1-2 days
Specimen Required: Collect:  and Transport: Cervical brush in HPV Digene Collection Kit (cervical brush and specimen transport medium) ARUP Supply #12578.

Transport:  Cervical brush in HPV Digene Kit specimen transport media at 2-8°C. Transport each specimen vial in an individual sealed bag.

Remarks:  Vaginal specimens are not recommended due to limited clinical correlative data.

Unacceptable Conditions:  Swabs or specimens in any other transport media. Urethral swabs. For specimens in ThinPrep® Pap Test transport media, refer to test code 0060750;  for specimens in SurePath® Pap specimen transport media, refer to test code 0060744.  Samples other than cervical are not acceptable for children under age 12.

Stability:  Digene transport medium: Ambient: 2 weeks; Refrigerated: 3 weeks; Frozen: 3 months
Reference Interval:
Negative
 
Test Number Components Reference Interval
 Human Papillomavirus (HPV) DNA Probe, High Risk Only  Negative

Interpretive Data: A high-risk HPV test detects HPV genotypes: 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59 and 68, which are associated with cervical cancer and its precursor lesions. However, cross-reactions with other genotypes may occur.  Results should be correlated with cytologic/histologic findings.  Sensitivity may be affected by cellularity of specimen.
Note: A negative result does not rule out the presence of an HPV genotype absent from the test panel, a low level infection, or specimen sampling error. 
CPT Code(s): 87621
 
 

 

 

 
All ARUP Sites:        www.aruplab.com     ·     www.arupconsult.com     ·     www.arup.utah.edu     ·     www.childx.org     ·     www.utahblood.org