ARUP's Laboratory Test Directory

Parvovirus B 19 Antibody, IgM : 0065122

Mnemonic: PARVO M

Methodology: Enzyme-Linked Immunosorbent Assay
Performed: Sun-Sat
Reported: 1-3 days
Specimen Required: Collect:  One 4 mL serum separator tube. Also acceptable: 3 mL lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin).

Transport:  0.5 mL serum or plasma at 2-8°C. (Min: 0.2 mL)  Submit specimen in an ARUP Standard Transport Tube.

Pediatric Collection/Transport:  0.1 mL serum or plasma at 2-8°C.

Remarks:  Separate serum or plasma from cells ASAP. Acute and convalescent specimens must be labeled as such; parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Please mark specimen plainly as "acute" or "convalescent."  

Unacceptable Conditions:  Heat-inactivated, hyperlipemic, icteric, hemolyzed, or contaminated specimens.

Stability:  After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval:
0.89 IV or less: Negative - No significant level of detectable Parvovirus B19 IgM antibody.
0.90-1.10 IV: Equivocal - Repeat testing in 10-14 days may be helpful.
1.11 IV or greater: Positive - IgM antibody to Parvovirus B19 detected, which may indicate a current or recent infection.  However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection.
Interpretive Data: The best evidence for current infection is a significant change on two appropriately timed specimens, where both tests are done in the same laboratory at the same time.

Appearance of an IgM antibody response normally occurs 7 to 14 days after the onset of disease. Testing immediately post-exposure is of no value without a later convalescent specimen. A residual IgM response may be distinguished from early IgM response to infection by testing sera from patients three to four weeks later for changing levels of specific IgM antibodies.
CPT Code(s): 86747
 
 

 

 

 
All ARUP Sites:        www.aruplab.com     ·     www.arupconsult.com     ·     www.arup.utah.edu     ·     www.childx.org     ·     www.utahblood.org