ARUP's Laboratory Test Directory
| 0060818: Human Papillomavirus (HPV) DNA Probe, High Risk, Cervical Brush (Digene) with Reflex to Genotyping |
| Test Mnemonic: HPV-HI R | |
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Methodology: Nucleic Acid Probe/Polymerase Chain Reaction
Performed: Tue, Thur Reported: 2-7 days |
| Specimen Required: | |
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Collect: and Transport: Cervical brush in HPV Digene Collection Kit (cervical brush and specimen transport medium) ARUP Supply #12578.
Transport: Cervical brush in HPV Digene Kit specimen transport media at 2-8°C. Submit specimen according to Biological Substance, Category B, shipping guidelines. Pediatric Collection/Transport: Submit specimen according to Biological Substance, Category B, shipping guidelines. Remarks: Vaginal specimens are not recommended due to limited clinical correlative data. Unacceptable Conditions: Swabs or specimens in any other transport media. Urethral swabs. For specimens in ThinPrep® Test transport media refer to test code 0060816; for specimens in SurePath® Test transport media refer to test code 0060817. Samples other than cervical are not acceptable for children under age 12. Stability: Ambient: 2 weeks; Refrigerated: 3 weeks; Frozen: 3 months |
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| Interpretive Data: | |
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Test Information: The high-risk HPV test detects HPV genotypes 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, and 68, which are associated with cervical cancer and its precursor lesions. However, cross-reactions with other genotypes may occur. Results should be correlated with cytologic and histologic findings. Sensitivity may be affected by cellularity of specimen. Please refer to Statement B in the Compliance Statements section in the front of the Laboratory Test Directory. |
| Note: | |
| If the Human Papillomavirus (HPV) DNA Probe test is positive Genotyping is performed. Genotyping is not performed on specimens yielding negative or equivocal results on the Human Papillomavirus (HPV) DNA Probe test. |
| CPT Code(s): | |
| 87621 DNA Probe; if reflexed, add 87621 x10 |