ARUP's Laboratory Test Directory

0060391: Antibiotic Level, Ciprofloxacin

Test Mnemonic: MA CIPRO
Methodology: Bioassay

Performed: Sun-Sat

Reported: 1-2 days

Specimen Required:  
Collect: One 7 mL plain red. Aseptically remove serum to a sterile tube and freeze.

Transport: 3 mL serum, frozen. (Min: 1 mL)

Pediatric Collection/Transport: 0.25 mL serum, frozen.

Remarks: Required information includes time and date of collection, time of last dose, and list of all antibiotics that the patient is receiving or has received in the past 48 hours.

Unacceptable Conditions: Delayed transport of nonfrozen specimens.  Inadequate information.  Plasma.

Stability: Ambient: 2 hours; Refrigerated: 24 hours; Frozen: 1 week

Reference Interval:
1.6-4.8 µg/mL

Interpretive Data:
Normal therapeutic peak serum concentration for ciprofloxacin is 1.6-4.8 µg/mL. Trough serum concentration is not well established.

For bioassay measurements, the presence of other antimicrobial agents may interfere with the assay.  Other factors that may influence antimicrobial levels include inherent differences among patients and their underlying physical conditions as well as the dose and route of administration of the antimicrobial agent.



Note:
Please include time of last dose, and list of all antibiotics that the patient is receiving or has received in the past 48 hours.  This information is important for laboratory handling and essential for subsequent physician interpretation of results. 

CPT Code(s):
80299