Reference Interval:
Minimum inhibitory concentration (MIC) without interpretation.
Minimum effective concentrations (MEC) without interpretation for the echinocandins.
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| Interpretive Data: |
Interpretive MIC breakpoints have not been established for mould. Experience to date indicates that amphotericin B MICs for most opportunistic mould isolates cluster between 0.5-2.0 µg/mL. However, for some species (eg, A. terreus) the MIC may range between 2-16 µg/mL. Filamentous fungi are usually not susceptible to 5-fluorocytosine or fluconazole and therefore are not reported. The echinocandins do not have activity against Fusarium species and therefore are not reported.
Susceptibility testing is performed by CLSI-approved broth microdilution method
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| Note: |
The following antifungal agents are tested: Amphotericin B, anidulafungin, caspofungin, fluconazole, 5-fluorocytosine, griseofulvin, itraconazole, micafungin, posaconazole, terbinafine, and voriconazole. Selective reporting by organism.
Testing is not performed on isolates from environmental sources. If isolate identification is not provided, identification will be performed at ARUP for an additional charge. An additional handling fee will be billed for all organisms submitted that are not in pure culture per specimen requirements.
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| CPT Code(s): |
87186
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Cross References: |
Fungal Susceptibility (Antimicrobial Susceptibility - Mould Susceptibility), Mould Susceptibility Panel (Antimicrobial Susceptibility - Mould Susceptibility), Susceptibility Testing (Antimicrobial Susceptibility - Mould Susceptibility) |
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