ARUP's Laboratory Test Directory

Mycobacterium tuberculosis Amplified Detection , CSF : 0060063
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Additional Technical Information
  


Mnemonic: MC MTDCSF

Methodology: Qualitative Transcription Mediated Amplification (Gen-Probe®)
Performed: Sun-Fri
Reported: 1-3 days
Specimen Required: Collect: CSF.

Specimen Preparation: Transfer 1 mL CSF to a sterile container. (Min: 0.5 mL)

Storage/Transport Temperature: Refrigerated.

Unacceptable Conditions: Bloody specimens.

Stability (collection to initiation of testing): Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 1 week
Reference Interval:
Negative - No Mycobacterium tuberculosis complex rRNA detected by transcription-mediated amplification.
Interpretive Data: This test is not FDA approved for specimens other than respiratory sources; however, this assay was validated at ARUP Laboratories for nonbloody CSF specimens.

The MTD test is specific for, but does not differentiate among members of the M. tuberculosis complex. M. celatum and M. terrae-like organisms will cross react if present at concentrations higher than 30 CFU/test. However, those species are rare clinical isolates. Specimens with high levels of nontuberculosis mycobacteria (greater than 1,000,000 cells/test) may cause low level positive MTD results when M. tuberculosis complex is not present.

See Compliance Statement B: www.aruplab.com/CS
CPT Code(s): 87556
Cross References: Amplified Direct Detection, MTD (Mycobacterium tuberculosis Amplified Detection , CSF) , Mycobacteria Culture (Mycobacterium tuberculosis Amplified Detection , CSF) , Mycobacterium tuberculosis Detection, NAA (Mycobacterium tuberculosis Amplified Detection , CSF) , TB Culture (Mycobacterium tuberculosis Amplified Detection , CSF)