ARUP's Laboratory Test Directory

0060055: Coxsackie B Virus Antibodies

Test Mnemonic: COX B
Methodology: Serum Neutralization Assay

Performed: Mon-Sat

Reported: 6-9 days

Specimen Required:  
Collect: One 6 mL SST or plain red.

Transport: 3 mL serum at 2-8°C. Also acceptable: CSF. (Min: 1 mL)  Submit specimen in an ARUP Standard Transport Tube.

Pediatric Collection/Transport: 0.25 mL serum at 2-8°C.

Remarks: Separate serum from cells ASAP. Acute and convalescent specimens must be labeled as such; parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of acute specimens. Please mark specimens plainly as "acute" or "convalescent."

Unacceptable Conditions: Plasma.

Stability: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year

Reference Interval:
Coxsackie B1: Less than 1:10
Coxsackie B2: Less than 1:10
Coxsackie B3: Less than 1:10
Coxsackie B4: Less than 1:10
Coxsackie B5: Less than 1:10
Coxsackie B6: Less than 1:10

Interpretive Data:
Single positive antibody titers of greater than or equal to 1:80 may indicate past or current infection.  Seroconversion or an increase in titers between acute and convalescent sera of at least fourfold is considered strong evidence of current or recent infection.



Note:
The clinical significance and criteria for interpretation of results from CSF have not been established.

CPT Code(s):
86658 x6 Coxsackie (B1, B2, B3, B4, B5, and B6)

 

 

 
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