ARUP's Laboratory Test Directory

0060054: Poliovirus Antibodies

Test Mnemonic: POLIO
Methodology: Serum Neutralization Assay

Performed: Mon-Sat

Reported: 6-9 days

Specimen Required:  
Collect: One 6 mL SST or plain red.

Transport: 1 mL serum at 2-8°C. Also acceptable: CSF. (Min: 1 mL)

Pediatric Collection/Transport: 0.25 mL serum or CSF at 2-8°C.

Remarks: Separate serum from cells ASAP.

Unacceptable Conditions: Plasma samples.

Stability: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year

Reference Interval:
Poliovirus 1: Less than 1:10
Poliovirus 2: Less than 1:10
Poliovirus 3: Less than 1:10*

Interpretive Data:
The presence of poliovirus antibodies may represent prior immunization or acute infection. The clinical significance of and the criteria for interpretation of results may require consultation with an Infectious Diseases Specialist.
 
*In immunized individuals, the significance of a low antibody titer to poliovirus 3 (the least immunogenic vaccine serotype) is unclear.



CPT Code(s):
86658 x3 Poliovirus (1, 2, and 3)

 

 

 
All ARUP Sites:        www.aruplab.com     ·     www.arupconsult.com     ·     www.arup.utah.edu     ·     www.childx.org     ·     www.utahblood.org