ARUP's Laboratory Test Directory

Poliovirus Antibodies : 0060054

Mnemonic: POLIO

Methodology: Serum Neutralization Assay
Performed: Mon-Sat
Reported: 6-9 days
Specimen Required: Collect:  One 6 mL serum separator tube or plain red.

Transport:  1 mL serum at 2-8°C. Also acceptable: CSF. (Min: 1 mL)

Pediatric Collection/Transport:  0.25 mL serum or CSF at 2-8°C.

Remarks:  Separate serum from cells ASAP.

Unacceptable Conditions:  Plasma samples.

Stability:  Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year
Reference Interval:
Poliovirus 1: Less than 1:10
Poliovirus 2: Less than 1:10
Poliovirus 3: Less than 1:10*
Interpretive Data: The presence of poliovirus antibodies may represent prior immunization or acute infection. The clinical significance of and the criteria for interpretation of results may require consultation with an Infectious Diseases Specialist.
 
*In immunized individuals, the significance of a low antibody titer to poliovirus 3 (the least immunogenic vaccine serotype) is unclear.
CPT Code(s): 86658 x3 Poliovirus (1, 2, and 3)
 
 

 

 

 
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