ARUP's Laboratory Test Directory
| 0055594: T-Cell Clonality Assessment by Restriction Fragment-Southern Blot Hybridization, Tissue |
| Test Mnemonic: TCRFSBHT | |
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#ExistMethodology>
Methodology: Restriction Fragment Southern Blot Hybridization
*ExistMethodology> #ExistPerformed> Performed: DNA isolation: Sun-Sat; Assay: Varies *ExistPerformed> #ExistReported> Reported: 7-14 days *ExistReported> |
| Specimen Required: | |
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#ExistCollect>
Collect: Fresh tissue. Freeze immediately.
*ExistCollect> #ExistTransport> Transport: 100 mg or 0.5-2.0 cm3 tissue, frozen on dry ice. *ExistTransport> #ExistConditions> Unacceptable Conditions: Paraffin samples. *ExistConditions> #ExistStability> Stability: Ambient: Unacceptable; Refrigerated: 2 hours; Frozen: 1 year *ExistStability> |
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| Reference Interval: |
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#ExistRefRange> Negative: A monoclonal T-cell population is not detected. Positive: A monoclonal T-cell population is detected. (Monoclonal T-cell receptor beta gene rearrangement identified by Southern blot analysis.) *ExistRefRange> |
| Interpretive Data: | |
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#ExistInterpData>
By report
Please refer to Statement B in the Compliance Statements section in the front of the Laboratory Test Directory. *ExistInterpData> |
| Note: | |
| A positive result indicates the presence of monoclonal T-cell population within the sample. A negative result does not entirely exclude the presence of a T-cell receptor gene rearrangement (or monoclonal T-cell population) in the sample. |
| CPT Code(s): | |
| 83907 Lysis; 83891 Isolation; 83892 x3 Digestion; 83894 Gel electrophoresis; 83897 Southern transfer; 83896 Nucleic acid probe; 83912 Interpretation and report - Additional CPT code modifiers may be required for procedures performed to test for oncologic or inherited disorders. |