Reference Interval:
Negative: A monoclonal T-cell population is not detected.
Positive: A monoclonal T-cell population is detected.
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| Interpretive Data: |
By report
Please refer to Statement B in the Compliance Statements section in the front of the Laboratory Test Directory.
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| Note: |
A positive result indicates the presence of monoclonal T-cell population within the sample. A negative result does not entirely exclude the presence of a T-cell receptor gamma gene rearrangement (or monoclonal T-cell population) in the sample. Negative PCR screening studies should be terminally analyzed by restriction fragment Southern blot hybridization (RF-SBH) to definitively exclude T-cell monoclonality. This is not automatically performed unless otherwise stipulated and can be performed using fresh or frozen tissue.
For confirmation testing refer to T-Cell Clonality Assessment by Restriction Fragment Southern Blot Hybridization, Tissue (0055594).
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| CPT Code(s): |
83907 Lysis; 83891 Isolation; 83898 x6 Amplification; 83896 x3 Nucleic Acid Probes; 83909 Capillary electrophoresis; 83912 Interpretation and report - Additional CPT code modifiers may be required for procedures performed to test for oncologic or inherited disorders.
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