ARUP's Laboratory Test Directory
| 0055568: T-Cell Clonality Screening Assay by PCR, Tissue |
| Test Mnemonic: T CELL-T | |
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Methodology: Polymerase Chain Reaction/Fragment Analysis
Performed: DNA isolation: Sun-Sat; Assay: Varies Reported: 7-10 days |
| Specimen Required: | |
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Collect: Fresh tissue. Freeze immediately.
Transport: 100 mg or 0.5-2.0 cm3 tissue, frozen on dry ice. Stability: Ambient: Unacceptable; Refrigerated: 2 hours; Frozen: 1 year |
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| Reference Interval: |
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Negative: A monoclonal T-cell population is not detected. Positive: A monoclonal T-cell population is detected. |
| Interpretive Data: | |
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By report
Please refer to Statement B in the Compliance Statements section in the front of the Laboratory Test Directory. |
| Note: | |
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A positive result indicates the presence of monoclonal T-cell population within the sample. A negative result does not entirely exclude the presence of a T-cell receptor gamma gene rearrangement (or monoclonal T-cell population) in the sample. Negative PCR screening studies should be terminally analyzed by restriction fragment Southern blot hybridization (RF-SBH) to definitively exclude T-cell monoclonality. This is not automatically performed unless otherwise stipulated and can be performed using fresh or frozen tissue. For confirmation testing refer to T-Cell Clonality Assessment by Restriction Fragment Southern Blot Hybridization, Tissue (0055594). |
| CPT Code(s): | |
| 83907 Lysis; 83891 Isolation; 83898 x6 Amplification; 83896 x3 Nucleic Acid Probes; 83909 Capillary electrophoresis; 83912 Interpretation and report - Additional CPT code modifiers may be required for procedures performed to test for oncologic or inherited disorders. |