ARUP's Laboratory Test Directory

0055557: bcl-1/JH, t(11;14) Translocation by PCR, Fluid

Test Mnemonic: BCL1-F
Methodology: Polymerase Chain Reaction

Performed: DNA isolation: Sun-Sat; Assay: Varies

Reported: 2-7 days

Specimen Required:  
Collect: Two 5 mL lavender (EDTA) or pink (K2EDTA), one 10 mL yellow (ACD Solution A), or 3 mL bone marrow in lavender (EDTA) or pink (K2EDTA).

Transport: 10 mL whole blood or 3 mL bone marrow at 2-8°C. (Min: 3 mL)  Also acceptable: CSF and pleural fluid.

Pediatric Collection/Transport: 1 mL whole blood or 1 mL bone marrow at 2-8°C.

Unacceptable Conditions: Serum, frozen whole blood, or clotted blood.  Severely hemolyzed specimens.

Stability: Ambient: 24 hours; Refrigerated: 5 days; Frozen: Unacceptable

Reference Interval:
Negative: bcl-1/JH gene rearrangement is not detected.
Positive: bcl-1/JH gene rearrangement is detected.

Interpretive Data:
By report

Please refer to Statement B in the Compliance Statements section in the front of the Laboratory Test Directory.



Note:
A positive result indicates the presence of a bcl-1/JH t(11;14) chromosomal translocation.  A negative result does not entirely exclude the presence of a bcl-1/JH chromosomal t(11;14) translocation.

CPT Code(s):
83891 Isolation; 83898 x4 Amplification; 83894 x3 Gel separation; 83912 Interpretation and report - Additional CPT code modifiers may be required for procedures performed to test for oncologic or inherited disorders.
  

 

 

 
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