#ExistInterpData>Neutrophil-associated antibodies may cause neutropenia in various autoimmune disorders including Felty's syndrome, SLE and drug-induced neutropenia. Febrile transfusion reactions and isoimmune neonatal neutropenia may also be caused by antibodies to neutrophil-specific antigens or HLA antigens.
A positive result on this test is not definitive for specific anti-neutrophil antibodies, since anti-HLA antibodies and immune complexes may also cause a positive result. The results of this test should be correlated to clinical history and other data.
See Compliance Statement A: www.aruplab.com/CS
||Circulating antibodies in patient's serum are measured by flow cytometry after incubation with normal neutrophils. Values greater than 2 standard deviations of a normal control population are interpreted as "weakly positive" and greater than 3 standard deviations as "positive".
This test should not be confused with Anti-Neutrophil Cytoplasmic Antibody, IgG (0050811 - ANCA).
||Anti-Granulocyte Antibodies (Neutrophil-Associated Antibodies), Anti-Neutrophil Antibodies (Neutrophil-Associated Antibodies), Granulocyte Ab (Neutrophil-Associated Antibodies), Neutrophil Antibody (Neutrophil-Associated Antibodies)