ARUP's Laboratory Test Directory
| 0055506: Anti-Neutrophil Antibody |
| Test Mnemonic: ANTI-NEU | |
|
Methodology: Flow Cytometry
Performed: Mon, Wed, Fri Reported: 1-5 days |
| Specimen Required: | |
|
Collect: One 10 mL plain red or SST.
Transport: 3 mL serum, frozen (on dry ice). (Min: 0.5 mL) Submit specimen in an ARUP Standard Transport Tube. For Salt Lake City clients, send 3 mL serum ASAP at 2-8°C. Pediatric Collection/Transport: 0.5 mL serum, frozen. For Salt Lake City clients, send 0.5 mL serum ASAP at 2-8°C. Remarks: Collect blood in a clot tube or separator tube and remove serum from cells. Stability: Refrigerated: 3 days; Frozen: 1 month |
|
| Reference Interval: |
| Negative |
| Interpretive Data: | |
|
Anti-neutrophil antibody has been implicated in causing the neutropenia of various autoimmune disorders, including Felty syndrome, systemic lupus erythematosus (SLE), and drug-induced neutropenia. Isoimmune destruction may be caused by antibodies to neutrophil-specific antigens and HLA antigens in febrile transfusion reactions and isoimmune neonatal neutropenia. Circulating antibodies in patient's serum are measured by flow cytometry after incubation with normal neutrophils. Values greater than 2 standard deviations of the control population are interpreted as "weakly positive" and greater than 3 standard deviations as "positive."
Please refer to Statement A in the Compliance Statements section in the front of the Laboratory Test Directory. |
| CPT Code(s): | |
| 86021 |