ARUP's Laboratory Test Directory

Cyclic Citrullinated Peptide Antibody, IgG : 0055256

Mnemonic: CCP IGG

Methodology: Enzyme-Linked Immunosorbent Assay
Performed: Sun-Sat
Reported: 1-2 days
Specimen Required: Collect:  One 4 mL serum separator tube.

Transport:  1 mL serum at 2-8°C.  (Min: 0.5 mL)  Submit specimen in an ARUP Standard Transport Tube.

Pediatric Collection/Transport:  0.2 mL serum 2-8°C.

Remarks:  Separate from cells ASAP.

Unacceptable Conditions:  Severely lipemic, contaminated, or hemolyzed specimens.

Stability:  After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval:
< 20 EU:  Negative
20-39 EU: Weak positive
40-59 EU:  Moderate positive
³60 EU: Strong positive
Interpretive Data: Approximately 70% of patients with RA are positive for CCP IgG, while only 2% of random blood donors and disease controls are positive.  The diagnostic value of antibodies to CCP in juvenile rheumatoid arthritis patients has not been determined.
CPT Code(s): 86200
 
 

 

 

 
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