ARUP's Laboratory Test Directory

0055256: Cyclic Citrullinated Peptide Antibody, IgG

Test Mnemonic: CCP IGG
Methodology: Enzyme-Linked Immunosorbent Assay

Performed: Sun-Sat

Reported: 1-2 days

Specimen Required:  
Collect: One 4 mL SST.

Transport: 1 mL serum at 2-8°C.  (Min: 0.5 mL)  Submit specimen in an ARUP Standard Transport Tube.

Pediatric Collection/Transport: 0.2 mL serum 2-8°C.

Remarks: Separate from cells ASAP.

Unacceptable Conditions: Severely lipemic, contaminated, or hemolyzed specimens.

Stability: After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval:
< 20 EU:  Negative
20-39 EU: Weak positive
40-59 EU:  Moderate positive
³60 EU: Strong positive

Interpretive Data:
Approximately 70% of patients with RA are positive for CCP IgG, while only 2% of random blood donors and disease controls are positive.  The diagnostic value of antibodies to CCP in juvenile rheumatoid arthritis patients has not been determined.



CPT Code(s):
86200

 

 

 
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