ARUP's Laboratory Test Directory
| 0055256: Cyclic Citrullinated Peptide Antibody, IgG |
| Test Mnemonic: CCP IGG | |
|
Methodology: Enzyme-Linked Immunosorbent Assay
Performed: Sun-Sat Reported: 1-2 days |
| Specimen Required: | |
|
Collect: One 4 mL SST.
Transport: 1 mL serum at 2-8°C. (Min: 0.5 mL) Submit specimen in an ARUP Standard Transport Tube. Pediatric Collection/Transport: 0.2 mL serum 2-8°C. Remarks: Separate from cells ASAP. Unacceptable Conditions: Severely lipemic, contaminated, or hemolyzed specimens. Stability: After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles) |
|
| Reference Interval: |
|
< 20 EU: Negative 20-39 EU: Weak positive 40-59 EU: Moderate positive ³60 EU: Strong positive |
| Interpretive Data: | |
|
Approximately 70% of patients with RA are positive for CCP IgG, while only 2% of random blood donors and disease controls are positive. The diagnostic value of antibodies to CCP in juvenile rheumatoid arthritis patients has not been determined.
|
| CPT Code(s): | |
| 86200 |