ARUP's Laboratory Test Directory

F-Actin (Smooth Muscle) Antibody, IgG : 0055248

Mnemonic: ACTIN IGG

Methodology: Enzyme-Linked Immunosorbent Assay
Performed: Sun, Tue, Thu
Reported: 1-4 days
Specimen Required: Collect:  One 4 mL SST.

Transport:  1 mL serum at 2-8°C.  (Min: 0.5 mL) Submit specimen in an ARUP Standard Transport Tube.

Pediatric Collection/Transport:  0.25 mL serum at 2-8°C.

Remarks:  Separate serum from cells ASAP.

Unacceptable Conditions:  Hemolyzed, lipemic, contaminated, or heat-inactivated specimens.

Stability:  After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval:
19 Units or less: Negative
20-30 Units: Weak Positive - Suggest repeat testing in two to three weeks with fresh specimen.
31 Units or greater: Positive - Suggestive of autoimmune hepatitis or chronic active hepatitis.
Interpretive Data: F-actin antibodies have been shown to have greater sensitivity and specificity for autoimmune liver disease than anti-smooth muscle antibodies.
CPT Code(s): 83516
 
 

 

 

 
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