ARUP's Laboratory Test Directory
| 0055248: F-Actin (Smooth Muscle) Antibody, IgG |
| Test Mnemonic: ACTIN IGG | |
|
Methodology: Enzyme-Linked Immunosorbent Assay
Performed: Sun, Tue, Thu Reported: 1-4 days |
| Specimen Required: | |
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Collect: One 4 mL SST.
Transport: 1 mL serum at 2-8°C. (Min: 0.5 mL) Submit specimen in an ARUP Standard Transport Tube. Pediatric Collection/Transport: 0.25 mL serum at 2-8°C. Remarks: Separate serum from cells ASAP. Unacceptable Conditions: Hemolyzed, lipemic, contaminated, or heat-inactivated specimens. Stability: After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles) |
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| Reference Interval: |
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19 Units or less: Negative 20-30 Units: Weak Positive - Suggest repeat testing in two to three weeks with fresh specimen. 31 Units or greater: Positive - Suggestive of autoimmune hepatitis or chronic active hepatitis. |
| Interpretive Data: | |
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F-actin antibodies have been shown to have greater sensitivity and specificity for autoimmune liver disease than anti-smooth muscle antibodies.
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| CPT Code(s): | |
| 83516 |