ARUP's Laboratory Test Directory

Liver-Kidney Microsome - 1 Antibody, IgG : 0055241

Mnemonic: LKM1 IGG

Methodology: Enzyme-Linked Immunosorbent Assay
Performed: Sun, Tue, Thu
Reported: 1-4 days
Specimen Required: Collect:  One 4 mL serum separator tube.

Transport:  1 mL serum at 2-8°C.  (Min: 0.5 mL)  Submit specimen in an ARUP Standard Transport Tube.

Pediatric Collection/Transport:  0.5 mL serum at 2-8°C. 

Remarks:  Separate serum from cells ASAP.

Unacceptable Conditions:  Hemolyzed, lipemic, contaminated, or heat-inactivated specimens.

Stability:  After separation from cells:  Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval:
0.0-20.0 U: Negative
20.1-24.9 U: Equivocal
Greater than or equal to 25.0 U: Positive
Interpretive Data: A positive result indicates the presence of IgG antibodies to recombinant human P450 2D6 and suggests the possibility of autoimmune hepatitis, type 2.  A negative LKM-1 does not rule out the presence of autoimmune hepatitis, type 2.
CPT Code(s): 86376
 
 

 

 

 
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