ARUP's Laboratory Test Directory
| 0055241: Liver-Kidney Microsome - 1 Antibody, IgG |
| Test Mnemonic: LKM1 IGG | |
|
Methodology: Enzyme-Linked Immunosorbent Assay
Performed: Sun, Tue, Thu Reported: 1-4 days |
| Specimen Required: | |
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Collect: One 4 mL SST.
Transport: 1 mL serum at 2-8°C. (Min: 0.5 mL) Submit specimen in an ARUP Standard Transport Tube. Pediatric Collection/Transport: 0.5 mL serum at 2-8°C. Remarks: Separate serum from cells ASAP. Unacceptable Conditions: Hemolyzed, lipemic, contaminated, or heat-inactivated specimens. Stability: After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles) |
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| Reference Interval: |
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0.0-20.0 U: Negative 20.1-24.9 U: Equivocal Greater than or equal to 25.0 U: Positive |
| Interpretive Data: | |
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A positive result indicates the presence of IgG antibodies to recombinant human P450 2D6 and suggests the possibility of autoimmune hepatitis, type 2. A negative LKM-1 does not rule out the presence of autoimmune hepatitis, type 2.
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| CPT Code(s): | |
| 86376 |