ARUP's Laboratory Test Directory

0055235: Soluble Liver Antigen Antibody, IgG

Test Mnemonic: SLA
Methodology: Enzyme-Linked Immunosorbent Assay

Performed: Sun, Tue, Thu

Reported: 1-4 days

Specimen Required:  
Collect: One 4 mL SST.

Transport: 1 mL serum at 2-8°C.  (Min: 0.5 mL)  Submit specimen in an ARUP Standard Transport Tube.

Pediatric Collection/Transport: 0.2 mL serum at 2-8°C. 

Unacceptable Conditions: Hemolyzed, lipemic, contaminated, or heat-inactivated specimens.

Stability: After separation from cells: Ambient: 2 days; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval:
0.0-20.0 U: Negative
20.1-24.9 U: Equivocal
Greater than or equal to 25.0 U: Positive

Interpretive Data:
The presence of SLA antibodies has almost 100% specificity for autoimmune hepatitis, although only 12-30% have these antibodies.  Thus, a negative SLA IgG test does not rule out autoimmune hepatitis.



CPT Code(s):
83516

 

 

 
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