ARUP's Laboratory Test Directory

Kappa/Lambda Quantitative Free Light Chains with Ratio, Serum : 0055167

Mnemonic: KAP/LAM F

Methodology: Quantitative Nephelometry
Performed: Mon-Fri
Reported: 1-4 days
Specimen Required: Collect: Serum separator tube.

Specimen Preparation: Remove serum from cells ASAP or within 2 hours of collection. Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature: Refrigerated.

Unacceptable Conditions: Plasma. Room temperature specimens.

Stability (collection to initiation of testing): After separation from cells: Ambient: 2 hours; Refrigerated: 1 week; Frozen: 2 weeks
Reference Interval:
 
Test Number Components Reference Interval
 Lambda Quantitative Free Light Chains, Serum 0.57-2.63 mg/dL
 Kappa Quantitative Free Light Chains, Serum 0.33 - 1.94 mg/dL
 Kappa/Lambda Free Light Chain Ratio, Serum 0.26-1.65

Note: This assay is highly sensitive to increasing concentrations of monoclonal free kappa or free lambda light chains in the serum of patients with evolving or relapsing myelomas.
CPT Code(s): 83883 x2
Cross References: Protein Electrophoresis, Serum with Reflex to IFE, Serum and Free Kappa and Lambda Light Chains, Serum (Kappa/Lambda Quantitative Free Light Chains with Ratio, Serum) , Protein Electrophoresis, with Interpretation Serum, With Reflex to IFE, Serum and Free Kappa Lambda Light Chains, Serum (Kappa/Lambda Quantitative Free Light Chains with Ratio, Serum)