Ordering Recommendation

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation

Multiple patient encounters should be avoided.

Collect

Serum separator tube. Multiple specimen tubes should be avoided. Specimens should be collected no sooner than 2- 3 weeks and no later than 6 months after an insect sting.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.65 mL serum to an ARUP Standard Transport Tube. (Min: 0.4 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Hemolyzed, icteric, or lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year

Methodology

Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Performed

Sun-Sat

Reported

1-3 days

Reference Interval

Allergens included: Honeybee Venom, Paper Wasp, White-Faced Hornet, Yellow-Faced Hornet, Yellow Jacket Venom.

Effective 02/18/2014

Reporting Range
(reported in kU/L)
Probability of IgE Mediated
Clinical Reaction
Class Scoring
Less than 0.10 No significant level detected 0
0.10 - 0.34 Clinical relevance undetermined 0/1
0.35 - 0.70 Low 1
0.71 - 3.50 Moderate 2
3.51 - 17.50 High 3
17.51 - 50.00 Very high 4
50.01 - 100.00 Very high 5
Greater than 100.00 Very high 6

Interpretive Data

Allergen results of 0.10-0.34 kU/L are intended for specialist use as the clinical relevance is undetermined. Even though increasing ranges are reflective of increasing concentrations of allergen-specific IgE, these concentrations may not correlate with the degree of clinical response or skin testing results when challenged with a specific allergen. The correlation of allergy laboratory results with clinical history and in vivo reactivity to specific allergens is essential. A negative test may not rule out clinical allergy or even anaphylaxis.

Compliance Category

FDA

Note

Hotline History

N/A

CPT Codes

86003 x5

Components

Component Test Code* Component Chart Name LOINC
0055039 Allergen, Insect, Honey Bee Venom IgE 6844-5
0055041 Allergen, Interp, Immunocap Score IgE 48767-8
0055046 Allergen, Insect, White-faced Hornet IgE 6280-2
0055048 Allergen, Insect, Paper Wasp IgE 6198-6
0055065 Allergen, Insect, YellowFaced Hornet IgE 6288-5
0055139 Allergen, Insect, Yellow Jacket Ven IgE 6740-5
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Stinging Insects
Allergens, Hymenoptera, Bee Venom Profile