ARUP's Laboratory Test Directory
| 0054445: Varicella-Zoster Virus Antibody, IgM by ELISA (CSF) |
| Test Mnemonic: VZMCSF | |
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Methodology: Enzyme-Linked Immunosorbent Assay
Performed: Mon-Fri Reported: 1-5 days |
| Specimen Required: | |
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Collect: CSF.
Transport: 0.5 mL CSF at 2-8°C. (Min: 0.3 mL) Submit specimen in an ARUP Standard Transport Tube. Remarks: CSF is the only acceptable specimen type. Unacceptable Conditions: Heat-inactivated or contaminated specimens. Stability: Ambient: 8 hours; Refrigerated: 2 weeks; Frozen: 1 year |
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| Reference Interval: |
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0.90 ISR or less: Negative - No significant level of IgM antibody to varicella-zoster virus detected. 0.91-1.09 ISR: Equivocal - Repeat testing in 10-14 days may be helpful. 1.10 ISR or greater: Positive - Significant level of IgM antibody to varicella-zoster virus detected, which may indicate current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection. |
| Interpretive Data: | |
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The detection of antibodies to varicella-zoster in CSF may indicate central nervous system infection. However, consideration must be given to possible contamination by blood or transfer of serum antibodies across the blood-brain barrier.
Please refer to Statement E in the Compliance Statements section in the front of the Laboratory Test Directory. |
| CPT Code(s): | |
| 86787 |