ARUP's Laboratory Test Directory

Varicella-Zoster Virus Antibody, IgM by ELISA (CSF) : 0054445

Mnemonic: VZMCSF

Methodology: Enzyme-Linked Immunosorbent Assay
Performed: Mon-Fri
Reported: 1-5 days
Specimen Required: Collect:  CSF.

Transport:  0.5 mL CSF at 2-8°C. (Min: 0.3 mL)  Submit specimen in an ARUP Standard Transport Tube.

Remarks:  CSF is the only acceptable specimen type.

Unacceptable Conditions:  Heat-inactivated or contaminated specimens.

Stability:  Ambient: 8 hours; Refrigerated: 2 weeks; Frozen: 1 year
Reference Interval:
0.90 ISR or less: Negative - No significant level of IgM antibody to varicella-zoster virus detected.
0.91-1.09 ISR: Equivocal - Repeat testing in 10-14 days may be helpful.
1.10 ISR or greater: Positive - Significant level of IgM antibody to varicella-zoster virus detected, which may indicate current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection.
Interpretive Data: The detection of antibodies to varicella-zoster in CSF may indicate central nervous system infection.  However, consideration must be given to possible contamination by blood or transfer of serum antibodies across the blood-brain barrier.

Please refer to Statement E in the Compliance Statements section in the front of the Laboratory Test Directory.
CPT Code(s): 86787
 
 

 

 

 
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