ARUP's Laboratory Test Directory

Cytomegalovirus, Quantitative PCR : 0051813

Mnemonic: CMV QNT

Ordering Recommendation: Preferred test for detecting cytomegalovirus infection and guiding posttransplant therapy.
Methodology: Quantitative Polymerase Chain Reaction
Performed: Sun-Sat
Reported: 1-3 days
Specimen Required: Collect: Lavender (EDTA) or pink (K2EDTA).

Specimen Preparation: Separate plasma from cells. Transfer 1 mL plasma to a sterile container. (Min: 0.5 mL).

Storage/Transport Temperature: Frozen.

Unacceptable Conditions: Serum. Heparinized specimens.

Stability (collection to initiation of testing): Ambient: 24 hours; Refrigerated: 5 days; Frozen: 1 year

Reference Interval:
Not detected
Interpretive Data: The quantitative range of this test is 2.6- 6.6 log copies/mL (390-3,900,000 copies/mL) or 2.4- 6.4 log IU/mL (227- 2,270,000 IU/mL). One IU/mL of CMV DNA is approximately 1.72 copies/mL.

A negative result (less than 2.6 log copies/mL [less than 390 copies/mL] OR less than 2.4 log IU/mL [less than 227 IU/mL]) does not rule out the presence of PCR inhibitors in the patient specimen or CMV DNA concentrations below the level of detection of the test. Inhibition may also lead to underestimation of viral quantitation.

See Compliance Statement A: www.aruplab.com/CS
Note: The limit of quantification for this DNA test is 2.6 log copies/mL (390 copies/mL) or 2.4 log IU/mL (227 IU/mL). If the test DID NOT DETECT the virus, the test result will be reported as "<2.6 log copies/mL (<390 copies/mL)" and "<2.4 log IU/mL (<227 IU/mL)."  If the test DETECTED the presence of the virus but was not able to accurately quantify the number of copies, the test result will be reported as "Not Quantified."
CPT Code(s): 87497