ARUP's Laboratory Test Directory
| 0051750: BRAF V600E Mutation with Reflex to MLH1 Promoter Methylation, Paraffin |
| Test Mnemonic: BRAF RFLX | |
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Methodology: Polymerase Chain Reaction/Fluorescence Resonance Energy Transfer Analysis
Performed: Sun-Sat Reported: 10-12 days |
| Specimen Required: | |
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Collect: Paraffin embedded, formalin-fixed tissue blocks.
Transport: 1 Paraffin embedded, formalin-fixed tissue block. Ship in cooled container during summer months. Unacceptable Conditions: Paraffin blocks with no tumor tissue remaining. Samples fixed in formalin substitute. Stability: Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable |
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| Reference Interval: | |||||||||
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| Interpretive Data: | |
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Refer to report. This test is performed pursuant to an agreement with Roche Molecular Systems, Inc. Please refer to Statement B in the Compliance Statements section in the front of the Laboratory Test Directory. |
| Note: | |
| The MLH1 methylation test will be performed if the BRAF V600E is negative. |
| CPT Code(s): | |
| 83907 Lysis; 83896 x2 Nucleic Acid Probes; 83898 Amplification; 83912 Interpretation and report; if reflexed, add 83896 x2 Nucleic Acid Probes; 83898 x2 Amplification; 83912 Interpretation and report. Additional CPT code modifiers may be required for procedures performed to test oncologic or inherited disorders. |