ARUP's Laboratory Test Directory

BRAF V600E Mutation with Reflex to MLH1 Promoter Methylation, Paraffin : 0051750

Mnemonic: BRAF RFLX

Methodology: Polymerase Chain Reaction/Fluorescence Resonance Energy Transfer Analysis
Performed: Sun-Sat
Reported: 10-12 days
Specimen Required: Collect:  Paraffin embedded, formalin-fixed tissue blocks.

Transport:  1 Paraffin embedded, formalin-fixed tissue block. Ship in cooled container during summer months.

Unacceptable Conditions:  Paraffin blocks with no tumor tissue remaining. Samples fixed in formalin substitute.

Stability:  Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable
Reference Interval:
 
Test Number Components Reference Interval
 BRAF V600E by PCR By report
0051747MLH1 Promoter Methylation, Paraffin By report

Interpretive Data: Refer to report.

This test is performed pursuant to an agreement with Roche Molecular Systems, Inc.

Please refer to Statement B in the Compliance Statements section in the front of the Laboratory Test Directory.
Note: The MLH1 methylation test will be performed if the BRAF V600E is negative. 
CPT Code(s): 83907 Lysis;  83896 x2 Nucleic Acid Probes; 83898 Amplification; 83912 Interpretation and report; if reflexed, add 83896 x2 Nucleic Acid Probes; 83898 x2 Amplification; 83912 Interpretation and report. Additional CPT code modifiers may be required for procedures performed to test oncologic or inherited disorders.
 
 

 

 

 
All ARUP Sites:        www.aruplab.com     ·     www.arupconsult.com     ·     www.arup.utah.edu     ·     www.childx.org     ·     www.utahblood.org